SCHEMBL12781985

SCHEMBL12781985

CC1C(=O)OC(COCc2ccccc2)C(F)C1C

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.43
CTRB1 P17538 1/20 0.38
NAAA Q02083 1/20 0.38
FASN P49327 1/20 0.38
TSHR P16473 2/20 0.37
PTPN1 P18031 2/20 0.36
CDC25B P30305 1/20 0.36
AKT1 P31749 1/20 0.36
BCHE P06276 1/20 0.35
ACHE P22303 1/20 0.35
ALDH1A1 P00352 1/20 0.35
CYP3A4 P08684 3/20 0.35
MAPT P10636 1/20 0.35
CYP2C19 P33261 1/20 0.35
TAAR1 Q96RJ0 1/20 0.35
TACR2 P21452 1/20 0.34
PLA2G6 O60733 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23773045 0.89 LMNA (0.47) LMNACTRB1NAAAFASNTSHR
SCHEMBL13449565 0.87 LMNA (0.46) LMNACTRB1NAAAFASNTSHR
SCHEMBL13449577 0.83 BCHE (0.45) LMNACTRB1NAAAPTPN1CDC25B
SCHEMBL31725358 0.80 BCHE (0.47) LMNACTRB1FASNTSHRAKT1
SCHEMBL17320856 0.78 BCHE (0.46) LMNAPTPN1CDC25BBCHEACHE
SCHEMBL4588458 0.76 BCHE (0.50) LMNACTRB1FASNPTPN1CDC25B
SCHEMBL16689647 0.76 BCHE (0.46) LMNACTRB1NAAAFASNTSHR
SCHEMBL12781983 0.74 SLC6A2 (0.40) LMNATSHRTAAR1TACR2
SCHEMBL20483781 0.74 BCHE (0.47) LMNACTRB1FASNTSHRPTPN1
SCHEMBL22579739 0.74 BCHE (0.47) LMNACTRB1FASNTSHRPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110059910-A1 Novel aromatic fluoroglycoside derivatives, pharmaceuticals comprising said compounds and the use thereof SANOFI-AVENTIS (FR) 2011-03-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110059910-A1 Novel aromatic fluoroglycoside derivatives, pharmaceuticals comprising said compounds and the use thereof SLC5A2, SLC5A1, SLC2A2 LMNA 4201/4885CTRB1 906/4885NAAA 3235/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.