Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.32 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11903413 | 0.85 | ALDH1A1 (0.39) | ALDH1A1HTTMAPTSMN1; SMN2HDAC1 | |
| SCHEMBL11902550 | 0.83 | HTT (0.45) | ALDH1A1HTTMAPTSMN1; SMN2HDAC1 | |
| SCHEMBL12786042 | 0.79 | ALDH1A1 (0.48) | ALDH1A1HTTMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL11903120 | 0.72 | PPARD (0.38) | ALDH1A1HTTMAPTPSDKMT2A | |
| SCHEMBL11903055 | 0.71 | HTT (0.42) | ALDH1A1HTTMAPTSMN1; SMN2LMNA | |
| SCHEMBL11902835 | 0.69 | EGLN1 (0.40) | LMNAHDAC1HDAC6GAAHDAC4 | |
| SCHEMBL11903226 | 0.67 | HDAC1 (0.39) | ALDH1A1SMN1; SMN2LMNAHDAC1HDAC6 | |
| SCHEMBL11902905 | 0.67 | HTT (0.47) | ALDH1A1HTTMAPTSMN1; SMN2LMNA | |
| SCHEMBL11918076 | 0.66 | CYP1A2 (0.41) | ALDH1A1MAPTSMN1; SMN2LMNABRD4 | |
| SCHEMBL11913408 | 0.65 | ALDH1A1 (0.44) | ALDH1A1HTTMAPTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011045561-A2 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2011-04-21 | — | — | WO | disclosed |