SCHEMBL1278770

SCHEMBL1278770

CC(C)(C)OC(=O)c1cc(N)cc(N)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.45
CA1 P00915 2/20 0.45
CA2 P00918 2/20 0.45
CA9 Q16790 2/20 0.45
CA14 Q9ULX7 1/20 0.45
SLC7A5 Q01650 1/20 0.42
ALOX15 P16050 1/20 0.40
GABRA1 P14867 1/20 0.40
GABRG2 P18507 1/20 0.40
GABRB3 P28472 1/20 0.40
GABRA3 P34903 1/20 0.40
GABRA2 P47869 1/20 0.40
NPC1 O15118 1/20 0.39
STAT3 P40763 2/20 0.38
GRM6 O15303 1/20 0.36
SRD5A1 P18405 1/20 0.36
NR1H2 P55055 1/20 0.36
ATAD2 Q6PL18 1/20 0.36
ELANE P08246 1/20 0.35
ABCG2 Q9UNQ0 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8122251 0.96 CA12 (0.45) CA12CA1CA2CA9CA14
SCHEMBL2721154 0.89 CA12 (0.46) CA12CA1CA2CA9CA14
SCHEMBL31647047 0.87 TP53 (0.40) CA12CA1CA2CA9CA14
SCHEMBL14505217 0.86 ELANE (0.40) CA12CA1CA2CA9CA14
SCHEMBL7058435 0.84 CA12 (0.47) CA12CA1CA2CA9CA14
SCHEMBL29634161 0.81 SLC7A5 (0.55) CA12CA1CA2CA9CA14
SCHEMBL381125 0.81 SLC7A5 (0.55) CA12CA1CA2CA9CA14
SCHEMBL19187377 0.81 NPC1 (0.42) CA12CA1CA2CA9CA14
SCHEMBL16406592 0.81 TPMT (0.48) CA12CA1CA2CA9CA14
SCHEMBL27996077 0.80 CA12 (0.42) CA12CA1CA2CA9CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115318113-A Nanofiltration membrane and preparation method and application thereof 清华大学 2022-11-11 CN claimed
WO-2024220676-A1 MRNA DEGRADERS AND METHODS OF USE THEREOF UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2024-10-24 WO disclosed
CN-115318113-B Nanofiltration membrane and preparation method and application thereof 清华大学 2023-10-31 CN disclosed
CN-111139087-B Liquid crystal photo-alignment agent, liquid crystal photo-alignment film, and preparation method and application thereof 常州市尚科新材料有限公司 2022-12-27 CN disclosed
CN-115318113-A Nanofiltration membrane and preparation method and application thereof 清华大学 2022-11-11 CN disclosed
CN-111139087-A Liquid crystal photo-alignment agent, liquid crystal photo-alignment film, and preparation method and application thereof 常州市尚科新材料有限公司 2020-05-12 CN disclosed
US-8901353-B2 Polyimide precursor, polyimide, and liquid crystal aligning agent NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2014-12-02 US disclosed
CN-102428121-B Polyimide precursor, polyimide, and liquid crystal aligning agent NISSAN CHEMICAL IND LTD 2014-05-28 CN disclosed
EP-1666972-B1 USE OF A COMPOSITION CONTAINING POLYAMIC ACID FOR FORMING AN ANTI-REFLECTIVE COATING NISSAN CHEMICAL IND LTD (JP) 2013-03-27 EP disclosed
CN-102428121-A Polyimide precursor, polyimide, and liquid crystal aligning agent NISSAN CHEMICAL IND LTD 2012-04-25 CN disclosed
US-20120088888-A1 POLYIMIDE PRECURSOR, POLYIMIDE, AND LIQUID CRYSTAL ALIGNING AGENT NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2012-04-12 US disclosed
US-7598182-B2 having monomers of pyromellitic acid, 3,5-diaminobenzoic acid; use in a lithography for forming photoresist pattern NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2009-10-06 US disclosed
US-20070004228-A1 Polyamide acid-containing composition for forming antireflective film NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2007-01-04 US disclosed
EP-1666972-A1 POLYAMIDE ACID-CONTAINING COMPOSITION FOR FORMING ANTIREFLECTIVE FILM Nissan Chemical Industries, Ltd. (JP) 2006-06-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120088888-A1 POLYIMIDE PRECURSOR, POLYIMIDE, AND LIQUID CRYSTAL ALIGNING AGENT PUF60, F13A1, F12 CA12 1392/4885CA1 247/4885CA2 1637/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.