SCHEMBL127882

SCHEMBL127882

NCCSSc1ccccn1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EHMT2 Q96KQ7 1/20 0.59
EHMT1 Q9H9B1 1/20 0.59
APOBEC3G Q9HC16 1/20 0.59
HRH1 P35367 2/20 0.42
ALDH1A1 P00352 4/20 0.42
MAPT P10636 3/20 0.39
KMT2A Q03164 3/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
TDP1 Q9NUW8 1/20 0.39
LMNA P02545 2/20 0.37
MEN1 O00255 2/20 0.36
PKM P14618 1/20 0.36
HDAC1 Q13547 1/20 0.36
HDAC2 Q92769 1/20 0.36
NOS3 P29474 1/20 0.35
NOS1 P29475 1/20 0.35
NOS2 P35228 1/20 0.35
PI4KA P42356 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29371176 1.00 EHMT2 (0.59) EHMT2EHMT1APOBEC3GHRH1ALDH1A1
Hydrochloric Acid SCHEMBL476479 0.98 EHMT2 (0.57) EHMT2EHMT1APOBEC3GHRH1ALDH1A1
Hydrochloric Acid SCHEMBL957295 0.98 EHMT2 (0.57) EHMT2EHMT1APOBEC3GHRH1ALDH1A1
Hydrochloric Acid SCHEMBL29421834 0.98 EHMT2 (0.57) EHMT2EHMT1APOBEC3GHRH1ALDH1A1
Hydrochloric Acid SCHEMBL3416002 0.98 EHMT2 (0.57) EHMT2EHMT1APOBEC3GHRH1ALDH1A1
Cysteamine SCHEMBL2637878 0.92 EHMT2 (0.50) EHMT2EHMT1APOBEC3GHRH1ALDH1A1
SCHEMBL1271908 0.89 EHMT2 (0.55) EHMT2EHMT1APOBEC3GHRH1ALDH1A1
SCHEMBL10802711 0.89 EHMT2 (0.55) EHMT2EHMT1APOBEC3GHRH1ALDH1A1
SCHEMBL11833495 0.88 EHMT2 (0.70) EHMT2EHMT1APOBEC3GALDH1A1MAPT
SCHEMBL3991936 0.87 EHMT2 (0.53) EHMT2EHMT1APOBEC3GHRH1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 885 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12514962-B2 Medical device comprising a coating for mitigation of formation and/or growth of biofilm CYTACOAT AB (SE) 2026-01-06 US claimed
CN-118240237-B Nano silicon dioxide-protein conjugate and preparation method thereof 烟台泰和新材高分子新材料研究院有限公司 2024-08-30 CN claimed
CN-118240237-A Nano silicon dioxide-protein conjugate and preparation method thereof 烟台泰和新材高分子新材料研究院有限公司 2024-06-25 CN claimed
CN-117797275-A Lipid-mesoporous silicon nano delivery carrier and preparation method thereof 河南工业大学 2024-04-02 CN claimed
EP-3442594-B1 BLOCK COPOLYMER FOR OVERCOMING DRUG RESISTANCE OF TUMOURS TO CHEMOTHERAPY, ITS POLYMER-DRUG CONJUGATE, PHARMACEUTICAL COMPOSITION CONTAINING THEM, METHOD OF PREPARATION AND USE THEREOF USTAV MAKROMOLEKULARNI CHEMIE AV CR V V I (CZ) 2024-02-07 EP claimed
CN-112121174-B Heparin nano drug carrying system for loading amino antitumor drug and preparation method thereof 南京健友生化制药股份有限公司 2023-05-23 CN claimed
CN-112402625-B Photosensitizer-loaded PEG (polyethylene glycol) heparin nano micelle and preparation method thereof 健进制药有限公司 2022-12-09 CN claimed
CN-111875653-A Disulfide bond-containing amphotericin B derivative and application thereof 深圳市儿童医院 2020-11-03 CN claimed
CN-108503718-B Hydroxyalkyl starch conjugate and preparation method and application thereof 华中科技大学 2020-03-20 CN claimed
EP-3442594-A1 BLOCK COPOLYMER FOR OVERCOMING DRUG RESISTANCE OF TUMOURS TO CHEMOTHERAPY, ITS POLYMER-DRUG CONJUGATE, PHARMACEUTICAL COMPOSITION CONTAINING THEM, METHOD OF PREPARATION AND USE THEREOF Ustav Makromolekularni Chemie AV CR, v.v.i. (CZ) 2019-02-20 EP claimed
WO-1998031734-A1 COMPOSITION AND METHOD FOR REGULATING THE ADHESION OF CELLS AND BIOMOLECULES TO HYDROPHOBIC SURFACES UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 1998-07-23 WO claimed
US-5516703-A FORMING A HYDROPHILIC SURFACE HAVING A SPECIFIC CHEMICAL REACTIVITY ON A HYDROPHOBIC SUBSTRATE THE UNIVERSITY OF UTAH (US) 1996-05-14 US claimed
EP-0589867-B1 SENSING SURFACES CAPABLE OF SELECTIVE BIOMOLECULAR INTERACTIONS, TO BE USED IN BIOSENSOR SYSTEMS PHARMACIA BIOSENSOR AB (SE) 1996-04-10 EP claimed
EP-0445813-B1 7-(Diphenylmethyl)oxy-9a-methoxymitosane and the preparation and use thereof BRISTOL MYERS SQUIBB CO (US) 1995-08-02 EP claimed
US-5436161-A Matrix coating for sensing surfaces capable of selective biomolecular interactions, to be used in biosensor systems PHARMACIA BIOSENSOR AB (SE) 1995-07-25 US claimed
US-5352798-A Intermediates for mitomycins; antitumor agents BRISTOL-MYERS SQUIBB COMPANY (US) 1994-10-04 US claimed
EP-0589867-A1 SENSING SURFACES CAPABLE OF SELECTIVE BIOMOLECULAR INTERACTIONS, TO BE USED IN BIOSENSOR SYSTEMS. PHARMACIA BIOSENSOR AB (SE) 1994-04-06 EP claimed
US-5242828-A SENSING SURFACES CAPABLE OF SELECTIVE BIOMOLECULAR INTERACTIONS, TO BE USED IN BIOSENSOR SYSTEMS PHARMACIA BIOSENSOR AB (SE) 1993-09-07 US claimed
EP-0445813-A1 7-(Diphenylmethyl)oxy-9a-methoxymitosane and the preparation and use thereof Bristol-Myers Squibb Company (US) 1991-09-11 EP claimed
WO-1990005303-A1 SENSING SURFACES CAPABLE OF SELECTIVE BIOMOLECULAR INTERACTIONS, TO BE USED IN BIOSENSOR SYSTEMS PHARMACIA AB (SE) 1990-05-17 WO claimed