SCHEMBL1271908

SCHEMBL1271908

NCCSSSc1ccccn1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EHMT2 Q96KQ7 1/20 0.55
EHMT1 Q9H9B1 1/20 0.55
APOBEC3G Q9HC16 1/20 0.55
ALDH1A1 P00352 5/20 0.40
HRH1 P35367 2/20 0.40
KMT2A Q03164 4/20 0.37
MAPT P10636 3/20 0.37
L3MBTL1 Q9Y468 3/20 0.37
NPC1 O15118 3/20 0.37
RAB9A P51151 3/20 0.37
TDP1 Q9NUW8 1/20 0.37
LMNA P02545 1/20 0.36
MEN1 O00255 3/20 0.35
PKM P14618 2/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
HPGD P15428 2/20 0.33
KIF11 P52732 1/20 0.33
TSHR P16473 1/20 0.33
USP2 O75604 1/20 0.33
GAA P10253 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29371176 0.89 EHMT2 (0.59) EHMT2EHMT1APOBEC3GALDH1A1HRH1
SCHEMBL127882 0.89 EHMT2 (0.59) EHMT2EHMT1APOBEC3GALDH1A1HRH1
Hydrochloric Acid SCHEMBL957295 0.87 EHMT2 (0.57) EHMT2EHMT1APOBEC3GALDH1A1HRH1
Hydrochloric Acid SCHEMBL3416002 0.87 EHMT2 (0.57) EHMT2EHMT1APOBEC3GALDH1A1HRH1
Hydrochloric Acid SCHEMBL476479 0.87 EHMT2 (0.57) EHMT2EHMT1APOBEC3GALDH1A1HRH1
Hydrochloric Acid SCHEMBL29421834 0.87 EHMT2 (0.57) EHMT2EHMT1APOBEC3GALDH1A1HRH1
Cysteamine SCHEMBL2637878 0.81 EHMT2 (0.50) EHMT2EHMT1APOBEC3GALDH1A1HRH1
SCHEMBL10802711 0.79 EHMT2 (0.55) EHMT2EHMT1APOBEC3GALDH1A1HRH1
SCHEMBL3736785 0.78 ALDH1A1 (0.69) EHMT2EHMT1APOBEC3GALDH1A1KMT2A
SCHEMBL3991936 0.77 EHMT2 (0.53) EHMT2EHMT1APOBEC3GALDH1A1HRH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260027147-A1 EXTRACELLULAR VESICLE-ASO CONSTRUCTS TARGETING CEBP/BETA LONZA SALES AG (CH) 2026-01-29 US disclosed
US-20250382613-A1 METHODS OF USING EXTRACELLULAR VESICLE-ASO TARGETING STAT6 LONZA SALES AG (CH) 2025-12-18 US disclosed
EP-4562156-A2 EXTRACELLULAR VESICLE-ASO CONSTRUCTS TARGETING CEBP/BETA Lonza Sales AG (CH) 2025-06-04 EP disclosed
CN-114728078-B Extracellular vesicles linked to molecules and uses thereof 隆萨销售股份公司 2025-05-16 CN disclosed
EP-4547259-A2 METHODS OF USING EXTRACELLULAR VESICLE-ASO TARGETING STAT6 Lonza Sales AG (CH) 2025-05-07 EP disclosed
CN-119948163-A CEBP/beta targeted extracellular vesicle-ASO constructs 隆萨销售股份有限公司 2025-05-06 CN disclosed
CN-119855597-A Methods of using STAT 6-targeted extracellular vesicles-ASOs 隆萨销售股份有限公司 2025-04-18 CN disclosed
US-20250115904-A1 EXTRACELLULAR VESICLE-ASO CONSTRUCTS TARGETING STAT6 LONZA SALES AG (CH) 2025-04-10 US disclosed
EP-4470619-A2 EXTRACELLULAR VESICLE-ASO CONSTRUCTS TARGETING STAT6 Lonza Sales AG (CH) 2024-12-04 EP disclosed
US-20240254481-A1 EXTRACELLULAR VESICLE-ASO CONSTRUCTS TARGETING STAT6 LONZA SALES AG (CH) 2024-08-01 US disclosed
US-20130217754-A1 PREVENTIVE OR THERAPEUTIC AGENT FOR FIBROSIS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2013-08-22 US disclosed
EP-2628798-A1 PROPHYLACTIC OR THERAPEUTIC AGENT FOR FIBROSIS Mie University (JP) 2013-08-21 EP disclosed
US-20110111501-A1 COMPLEX OF POLYSACCHARIDE AND DOUBLE-STRANDED RNA NAPA JENOMICS CO., LTD. (JP) 2011-05-12 US disclosed
US-20110034545-A1 DOUBLE-STRANDED LIPID-MODIFIED RNA HAVING HIGH RNA INTERFERENCE EFFECT OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2011-02-10 US disclosed
EP-2264167-A1 DOUBLE-STRANDED LIPID-MODIFIED RNA HAVING HIGH RNA INTERFERENCE EFFECT National Institute of Advanced Industrial Science and Technology (JP) 2010-12-22 EP disclosed
US-20100298411-A1 LIPID-MODIFIED DOUBLE-STRANDED RNA HAVING POTENT RNA INTERFERENCE EFFECT NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY 2010-11-25 US disclosed
EP-2226384-A1 COMPLEX OF POLYSACCHARIDE AND DOUBLE-STRANDED RNA National Institute of Advanced Industrial Science and Technology (JP) 2010-09-08 EP disclosed
EP-2217284-A2 LIPID-MODIFIED DOUBLE-STRANDED RNA HAVING POTENT RNA INTERFERENCE EFFECT National Institute of Advanced Industrial Science And Technology (JP) 2010-08-18 EP disclosed
WO-2009054551-A2 LIPID-MODIFIED DOUBLE-STRANDED RNA HAVING POTENT RNA INTERFERENCE EFFECT NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2009-04-30 WO disclosed
EP-1731615-A1 CYTOPLASMIC LOCALIZATION DNA AND RNA National Institute of Advanced Industrial Science and Technology (JP) 2006-12-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250115904-A1 EXTRACELLULAR VESICLE-ASO CONSTRUCTS TARGETING STAT6 STAT6, STAT1, STAT5B EHMT2 487/4885EHMT1 468/4885APOBEC3G 2105/4885
US-20250382613-A1 METHODS OF USING EXTRACELLULAR VESICLE-ASO TARGETING STAT6 STAT6, EXOSC5, STAT5B EHMT2 471/4885EHMT1 660/4885APOBEC3G 1963/4885
US-20260027147-A1 EXTRACELLULAR VESICLE-ASO CONSTRUCTS TARGETING CEBP/BETA CEBPZ, OSBP, DIS3 EHMT2 2828/4885EHMT1 2611/4885APOBEC3G 2537/4885
US-20100298411-A1 LIPID-MODIFIED DOUBLE-STRANDED RNA HAVING POTENT RNA INTERFERENCE EFFECT NSUN3, NSUN2, RNASE1 EHMT2 807/4885EHMT1 1349/4885APOBEC3G 877/4885
US-20110034545-A1 DOUBLE-STRANDED LIPID-MODIFIED RNA HAVING HIGH RNA INTERFERENCE EFFECT NSUN3, NSUN2, ADAR EHMT2 762/4885EHMT1 1341/4885APOBEC3G 813/4885
US-20110111501-A1 COMPLEX OF POLYSACCHARIDE AND DOUBLE-STRANDED RNA RNGTT, MAN2A1, ADAR EHMT2 3752/4885EHMT1 3749/4885APOBEC3G 1102/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.