Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.72 |
| ▸ | CA1 | P00915 | 1/20 | 0.72 |
| ▸ | CA2 | P00918 | 1/20 | 0.72 |
| ▸ | CA9 | Q16790 | 1/20 | 0.72 |
| ▸ | POLB | P06746 | 1/20 | 0.71 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.70 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.70 |
| ▸ | EPHX1 | P07099 | 10/20 | 0.68 |
| ▸ | RAB9A | P51151 | 8/20 | 0.68 |
| ▸ | NPC1 | O15118 | 7/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13756244 | 0.86 | EPHX1 (0.86) | CYP2C9CYP2C19EPHX1RAB9ANPC1 | |
| SCHEMBL22470431 | 0.86 | EPHX1 (0.57) | CA12CA1CA2CA9POLB | |
| SCHEMBL11594697 | 0.85 | CA12 (0.72) | CA12CA1CA2CA9POLB | |
| SCHEMBL11594698 | 0.85 | CA12 (0.72) | CA12CA1CA2CA9POLB | |
| SCHEMBL13756248 | 0.84 | EPHX1 (0.83) | CA12CA1CA2CA9CYP2C9 | |
| SCHEMBL672714 | 0.84 | CA12 (1.00) | CA12CA1CA2CA9POLB | |
| SCHEMBL28193805 | 0.83 | CA12 (0.58) | CA12CA1CA2CA9POLB | |
| SCHEMBL28565718 | 0.83 | CA12 (0.58) | CA12CA1CA2CA9POLB | |
| SCHEMBL4010742 | 0.82 | EPHX2 (0.66) | CA12CA1CA2CA9POLB | |
| SCHEMBL813709 | 0.81 | EPHX1 (1.00) | POLBCYP2C9CYP2C19EPHX1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8722742-B2 | Chemical compounds having antiviral activity against Dengue virus and other Flaviviruses | CENTRO DE INGENIERIA GENETICA Y BIOTECNOLOGIA (CU) | 2014-05-13 | — | — | US | disclosed |
| US-20110065686-A1 | CHEMICAL COMPOUNDS HAVING ANTIVIRAL ACTIVITY AGAINST DENGUE VIRUS AND OTHER FLAVIVIRUSES | CENTRO DE INGENIERIA GENETICA Y BIOTECNOLOGIA (CU) | 2011-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110065686-A1 | CHEMICAL COMPOUNDS HAVING ANTIVIRAL ACTIVITY AGAINST DENGUE VIRUS AND OTHER FLAVIVIRUSES | MAVS, EIF2AK2, ZC3HAV1 | CA12 4678/4885CA1 4834/4885CA2 4502/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.