Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 20/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14529836 | 1.00 | KIF11 (0.44) | KIF11 | |
| SCHEMBL17461286 | 0.91 | KIF11 (0.44) | KIF11 | |
| SCHEMBL14529520 | 0.91 | KIF11 (0.44) | KIF11 | |
| SCHEMBL14529833 | 0.86 | KIF11 (0.42) | KIF11 | |
| SCHEMBL13924026 | 0.84 | KIF11 (0.42) | KIF11 | |
| SCHEMBL13924045 | 0.84 | KIF11 (0.42) | KIF11 | |
| SCHEMBL14019816 | 0.84 | KIF11 (0.40) | KIF11 | |
| SCHEMBL12792780 | 0.83 | KIF11 (0.32) | KIF11 | |
| SCHEMBL14529538 | 0.82 | KIF11 (0.45) | KIF11 | |
| SCHEMBL17461277 | 0.80 | KIF11 (0.48) | KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2033959-B1 | Tetrahydropyranoquinoline derivatives | MERCK PATENT GMBH (DE) | 2011-04-27 | — | — | EP | disclosed |