Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12277746 | 0.91 | ALDH1A1 (0.37) | ALDH1A1 | |
| SCHEMBL18177592 | 0.87 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL18133625 | 0.85 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL12278300 | 0.85 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL19222467 | 0.83 | ALDH1A1 (0.37) | ALDH1A1 | |
| SCHEMBL12278268 | 0.83 | ALDH1A1 (0.37) | ALDH1A1 | |
| SCHEMBL10441966 | 0.83 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL13561929 | 0.83 | ALDH1A1 (0.41) | ALDH1A1 | |
| SCHEMBL21235799 | 0.82 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL12277651 | 0.80 | CYP2A6 (0.31) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2483367-B1 | ELECTROLUMINESCENT THIOPHENE DERIVATIVES | LOMOX LTD (GB) | 2015-09-16 | — | — | EP | disclosed |
| US-9006435-B2 | Electroluminescent thiophene derivatives | LOMOX LIMITED (GB) | 2015-04-14 | — | — | US | disclosed |
| US-9006435-B2 | Electroluminescent thiophene derivatives | LOMOX LIMITED (GB) | 2015-04-14 | — | — | US | disclosed |
| US-20120271052-A1 | ELECTROLUMINESCENT THIOPHENE DERIVATIVES | LOMOX LIMITED (GB) | 2012-10-25 | — | — | US | disclosed |
| US-20120271052-A1 | ELECTROLUMINESCENT THIOPHENE DERIVATIVES | LOMOX LIMITED (GB) | 2012-10-25 | — | — | US | disclosed |
| WO-2011039505-A1 | ELECTROLUMINESCENT THIOPHENE DERIVATIVES | LOMOX LIMITED (GB) | 2011-04-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120271052-A1 | ELECTROLUMINESCENT THIOPHENE DERIVATIVES | AR, NR2E3, NES | ALDH1A1 1235/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.