Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 6/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12797655 | 0.98 | CYP2A6 (0.45) | CYP2A6CYP1A2TDP1BCL2L1MCL1 | |
| SCHEMBL12797656 | 0.95 | CYP2A6 (0.42) | CYP2A6CYP1A2TDP1BCL2L1MCL1 | |
| SCHEMBL10031388 | 0.94 | CYP2A6 (0.52) | CYP2A6CYP1A2TDP1BCL2L1MCL1 | |
| SCHEMBL17037120 | 0.94 | CYP2A6 (0.52) | CYP2A6CYP1A2TDP1BCL2L1MCL1 | |
| SCHEMBL10031363 | 0.94 | CYP2A6 (0.52) | CYP2A6CYP1A2TDP1BCL2L1MCL1 | |
| SCHEMBL16978710 | 0.94 | BCL2L1 (0.41) | CYP2A6CYP1A2BCL2L1MCL1LMNA | |
| SCHEMBL12796848 | 0.93 | CYP2A6 (0.50) | CYP2A6CYP1A2TDP1BCL2L1MCL1 | |
| SCHEMBL12797658 | 0.92 | CYP2A6 (0.42) | CYP2A6CYP1A2TDP1BCL2L1MCL1 | |
| SCHEMBL18267821 | 0.91 | CYP2A6 (0.48) | CYP2A6CYP1A2TDP1BCL2L1MCL1 | |
| SCHEMBL18405844 | 0.91 | CYP2A6 (0.48) | CYP2A6CYP1A2TDP1BCL2L1MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9260451-B2 | Method for producing aromatic compound | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2016-02-16 | — | — | US | disclosed |
| EP-2483367-B1 | ELECTROLUMINESCENT THIOPHENE DERIVATIVES | LOMOX LTD (GB) | 2015-09-16 | — | — | EP | disclosed |
| US-20150239901-A1 | Method For Producing Aromatic Compound | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2015-08-27 | — | — | US | disclosed |
| US-9006435-B2 | Electroluminescent thiophene derivatives | LOMOX LIMITED (GB) | 2015-04-14 | — | — | US | disclosed |
| US-9006435-B2 | Electroluminescent thiophene derivatives | LOMOX LIMITED (GB) | 2015-04-14 | — | — | US | disclosed |
| US-20120271052-A1 | ELECTROLUMINESCENT THIOPHENE DERIVATIVES | LOMOX LIMITED (GB) | 2012-10-25 | — | — | US | disclosed |
| US-20120271052-A1 | ELECTROLUMINESCENT THIOPHENE DERIVATIVES | LOMOX LIMITED (GB) | 2012-10-25 | — | — | US | disclosed |
| WO-2011039505-A1 | ELECTROLUMINESCENT THIOPHENE DERIVATIVES | LOMOX LIMITED (GB) | 2011-04-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120271052-A1 | ELECTROLUMINESCENT THIOPHENE DERIVATIVES | AR, NR2E3, NES | CYP2A6 2867/4885CYP1A2 3437/4885TDP1 2043/4885 |
| US-20150239901-A1 | Method For Producing Aromatic Compound | TYR, XDH, CYP1A1 | CYP2A6 125/4885CYP1A2 8/4885TDP1 3801/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.