SCHEMBL12798

SCHEMBL12798

Cc1cccc(C(N)=O)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 8/20 1.00
HDAC8 Q9BY41 1/20 0.59
HDAC6 Q9UBN7 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.55
PARP15 Q460N3 1/20 0.55
PARP10 Q53GL7 1/20 0.55
DHODH Q02127 1/20 0.54
CSF1R P07333 1/20 0.54
FLT1 P17948 1/20 0.54
FLT3 P36888 1/20 0.54
ELANE P08246 1/20 0.54
TDP1 Q9NUW8 2/20 0.53
KCNK3 O14649 1/20 0.53
KCNH2 Q12809 1/20 0.53
KCNK9 Q9NPC2 1/20 0.53
MEN1 O00255 1/20 0.53
KMT2A Q03164 1/20 0.53
HPGD P15428 1/20 0.53
POLB P06746 2/20 0.52
CYP3A4 P08684 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13799999 1.00 PARP1 (1.00) PARP1HDAC8HDAC6SMN1; SMN2PARP15
Hydrochloric Acid SCHEMBL5089078 0.98 PARP1 (0.96) PARP1HDAC8HDAC6SMN1; SMN2PARP15
Hydrochloric Acid SCHEMBL4376573 0.98 PARP1 (0.96) PARP1HDAC8HDAC6SMN1; SMN2PARP15
Trimethylammonium SCHEMBL8962690 0.94 PARP1 (0.88) PARP1HDAC8HDAC6SMN1; SMN2PARP15
M-Xylene SCHEMBL1203037 0.93 PARP1 (0.88) PARP1HDAC8HDAC6SMN1; SMN2PARP15
Butane SCHEMBL3726601 0.92 PARP1 (0.85) PARP1HDAC8HDAC6SMN1; SMN2PARP15
SCHEMBL5605353 0.88 PARP1 (0.78) PARP1PARP15PARP10DHODHCSF1R
Pyridine SCHEMBL28203272 0.87 PARP1 (0.76) PARP1HDAC8HDAC6SMN1; SMN2DHODH
SCHEMBL27456729 0.87 PARP1 (0.76) PARP1HDAC8HDAC6SMN1; SMN2PARP15
P-Xylene SCHEMBL17907442 0.86 PARP1 (0.76) PARP1PARP15PARP10DHODHCSF1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2461 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12410174-B1 Small molecular inhibitors of sting signaling compositions and methods of use TYERELL IMMUNOTHERAPEUTICS INC (US) 2025-09-09 US claimed
CN-116584486-B Antibacterial agent and preparation method and application thereof 江西清晨纸业有限公司 2025-04-25 CN claimed
CN-119894490-A SPF potentiators and sunscreen formulations containing same 美国陶氏有机硅公司 2025-04-25 CN claimed
CN-119504475-A N-alkylamine compound, preparation method and application 南阳师范学院 2025-02-25 CN claimed
CN-119371298-A Method for efficiently synthesizing indenone compound 南阳师范学院 2025-01-28 CN claimed
CN-119343336-A 1, 4-Bis- (2-hydroxy-benzyl) -1,4, 7-triazacyclononane derivatives and similar compounds as ligands in iron (III) complexes for use as MRI contrast agents 伯拉考成像股份公司 2025-01-21 CN claimed
EP-3887375-B1 3-(PHENYLSULFONYL)-[1,2,3]TRIAZOLO[1,5A]QUINAZOLIN-5(4H)-ONE DERIVATIVES BioVersys AG (CH) 2024-11-20 EP claimed
US-20240376239-A1 COPOLYMER, PIEZOELECTRIC MATERIAL, PIEZOELECTRIC FILM, AND PIEZOELECTRIC ELEMENT TDK CORPORATION (JP) 2024-11-14 US claimed
CN-118696036-A PARP1 inhibitors 突触活化疗法股份有限公司 2024-09-24 CN claimed
US-20240246948-A1 BENZAMIDE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF CANCER CONTAINING SAME AS ACTIVE INGREDIENT HK INNO.N CORPORATION (KR) 2024-07-25 US claimed
WO-1994010842-A1 DEVICE FOR DEFENCE AGAINST INSECTS LARUS PHARMA S.R.L. (IT) 1994-05-26 WO claimed
WO-1993020693-A1 INSECT REPELLING CARRIER BAND GALLUCCI DANIEL (US) 1993-10-28 WO claimed
US-5207803-A METHOD FOR DYEING AROMATIC POLYAMIDE FIBROUS MATERIALS: N,N-DIETHYL(META-TOLUAMIDE) DYE CARRIER SPRINGS INDUSTRIES (US) 1993-05-04 US claimed
CN-1060126-A The colouring method of fibrous material SPRINGS IND INC (US) 1992-04-08 CN claimed
EP-0271713-A2 Method for preparing aqueous solutions containing chromogenic materials SAVYON DIAGNOSTICS LTD. (IL) 1988-06-22 EP claimed
EP-0253548-A2 Method for the determination of occult blood and chemical compositions therefor SAVYON DIAGNOSTICS LTD. (IL) 1988-01-20 EP claimed
CN-85103863-A Composition of insect-repellant soap and method 1986-11-05 CN claimed
EP-0090287-A1 Insect repellent BAYER AG (DE) 1983-10-05 EP claimed
US-4084056-A FROM AN AROMATIC AMIDE AND A GROUP IA OR IIA HYPOCHLORITE WITH A CARBAMATE SUBSTITUTED PHENOL AB BOFORS (SW) 1978-04-11 US claimed
US-3943152-A Method for preparing azines PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1976-03-09 US claimed