P-Xylene

P-Xylene

SCHEMBL17907442

Cc1ccc(C)cc1.NC(=O)c1cccc(C(N)=O)c1

nearest known ligand 0.76

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 9/20 0.76
DHODH Q02127 2/20 0.57
PARP15 Q460N3 2/20 0.55
PARP10 Q53GL7 2/20 0.55
TSHR P16473 2/20 0.52
POLB P06746 1/20 0.52
CYP3A4 P08684 1/20 0.52
MAPT P10636 1/20 0.52
CYP2C19 P33261 1/20 0.52
RECQL P46063 1/20 0.52
BLM P54132 1/20 0.52
PMP22 Q01453 1/20 0.52
HSD17B10 Q99714 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
MAP2K4 P45985 1/20 0.50
CES2 O00748 1/20 0.50
CES1 P23141 1/20 0.50
KIF11 P52732 1/20 0.50
TNKS O95271 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
M-Xylene SCHEMBL1203037 0.89 PARP1 (0.88) PARP1DHODHPARP15PARP10TSHR
SCHEMBL31021028 0.88 PARP1 (0.73) PARP1DHODHPARP15PARP10TSHR
SCHEMBL36694 0.88 PARP1 (0.73) PARP1DHODHPARP15PARP10TSHR
SCHEMBL13799999 0.86 PARP1 (1.00) PARP1DHODHPARP15PARP10TSHR
SCHEMBL12798 0.86 PARP1 (1.00) PARP1DHODHPARP15PARP10TSHR
SCHEMBL3727219 0.86 DHODH (0.71) PARP1DHODHMAP2K4CSF1RFLT1
Methane SCHEMBL688609 0.85 PARP1 (0.70) PARP1DHODHPARP15PARP10TSHR
Water SCHEMBL7768285 0.85 PARP1 (0.70) PARP1DHODHPARP15PARP10TSHR
Ammonia Solution, Strong SCHEMBL9121446 0.85 PARP1 (0.70) PARP1DHODHPARP15PARP10TSHR
Hydrochloric Acid SCHEMBL1367509 0.85 PARP1 (0.70) PARP1DHODHPARP15PARP10TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11254082-B2 Multi-layer tube UBE INDUSTRIES, LTD. (JP) 2022-02-22 US disclosed
US-10663092-B2 Multilayer tube UBE INDUSTRIES, LTD. (JP) 2020-05-26 US disclosed
EP-3042758-B1 LAMINATED TUBE UBE INDUSTRIES (JP) 2020-05-06 EP disclosed
EP-3461631-A1 MULTILAYER TUBE Ube Industries, Ltd. (JP) 2019-04-03 EP disclosed
EP-3192650-B1 LAYERED TUBE UBE INDUSTRIES (JP) 2019-01-23 EP disclosed
US-20170261133-A1 MULTILAYER TUBE UBE INDUSTRIES, LTD. (JP) 2017-09-14 US disclosed
EP-3192650-A1 LAYERED TUBE UBE Industries, Ltd. (JP) 2017-07-19 EP disclosed
US-20160214343-A1 MULTI-LAYER TUBE UBE INDUSTRIES, LTD. (JP) 2016-07-28 US disclosed
EP-3042758-A1 LAMINATED TUBE UBE Industries, Ltd. (JP) 2016-07-13 EP disclosed