Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.62 |
| ▸ | MET | P08581 | 7/20 | 0.60 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.57 |
| ▸ | CA12 | O43570 | 3/20 | 0.56 |
| ▸ | CA4 | P22748 | 3/20 | 0.56 |
| ▸ | CA6 | P23280 | 3/20 | 0.56 |
| ▸ | CA5A | P35218 | 3/20 | 0.56 |
| ▸ | CA7 | P43166 | 3/20 | 0.56 |
| ▸ | CA9 | Q16790 | 3/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.56 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.56 |
| ▸ | TTR | P02766 | 2/20 | 0.54 |
| ▸ | HTR7 | P34969 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.54 |
| ▸ | APP | P05067 | 3/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2832034 | 0.97 | MAOB (0.66) | MAOBMETEPHX2CA12CA4 | |
| SCHEMBL31588435 | 0.97 | MAOB (0.66) | MAOBMETEPHX2CA12CA4 | |
| SCHEMBL12731794 | 0.92 | CA12 (0.63) | MAOBMETEPHX2CA12CA4 | |
| SCHEMBL12731880 | 0.92 | MAOB (0.63) | MAOBMETEPHX2CA12CA4 | |
| SCHEMBL12731796 | 0.92 | MAOB (0.60) | MAOBMETEPHX2CA12CA4 | |
| SCHEMBL12731814 | 0.91 | TTR (0.60) | TTRAPPHSD17B10CYP1A2MAPT | |
| SCHEMBL12793445 | 0.89 | EPHX2 (0.56) | MAOBMETEPHX2CA12CA4 | |
| SCHEMBL12731820 | 0.87 | TTR (0.60) | TTRAPPHSD17B10MAPTDPP4 | |
| SCHEMBL12731894 | 0.87 | TTR (0.60) | TTRAPPHSD17B10MAPTDPP4 | |
| SCHEMBL12731797 | 0.85 | EPHX2 (0.53) | MAOBMETEPHX2CA12CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150246014-A1 | Derivatives of Propane Diyl Dicinnamate | ORX PHARMACEUTICAL CORPORATION (CA) | 2015-09-03 | — | — | US | disclosed |
| US-9061993-B2 | Derivatives of propane diyl dicinnamate | Toronto Institute of Pharmaceutical Technology (CA) | 2015-06-23 | — | — | US | disclosed |
| WO-2011041907-A1 | DERIVATIVES OF DI(PHENYLPROPANOID) GLYCEROL FOR THE TREATMENT OF CANCER | MACGREGOR ALEXANDER (CA) | 2011-04-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150246014-A1 | Derivatives of Propane Diyl Dicinnamate | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, DECR2, DECR1 | MAOB 4261/4885MET 142/4885EPHX2 1718/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.