Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 10/20 | 0.54 |
| ▸ | CCR6 | P51684 | 3/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11891923 | 1.00 | HPGDS (0.54) | HPGDSCCR6ABCB1CYP2D6HDAC4 | |
| SCHEMBL30438993 | 1.00 | HPGDS (0.54) | HPGDSCCR6ABCB1CYP2D6HDAC4 | |
| SCHEMBL19256704 | 0.80 | HPGDS (0.55) | HPGDSCCR6ABCB1CYP2D6HDAC4 | |
| SCHEMBL11028449 | 0.79 | HPGDS (0.53) | HPGDSCCR6ABCB1CYP2D6HDAC4 | |
| SCHEMBL21293948 | 0.79 | HPGDS (0.53) | HPGDSCCR6ABCB1CYP2D6HDAC4 | |
| SCHEMBL11025421 | 0.79 | HPGDS (0.53) | HPGDSCCR6ABCB1CYP2D6HDAC4 | |
| Hydrochloric Acid SCHEMBL19206937 | 0.78 | HPGDS (0.52) | HPGDSCCR6ABCB1CYP2D6HDAC4 | |
| Hydrochloric Acid SCHEMBL20599057 | 0.78 | HPGDS (0.52) | HPGDSCCR6ABCB1CYP2D6HDAC4 | |
| Hydrochloric Acid SCHEMBL11032862 | 0.78 | HPGDS (0.52) | HPGDSCCR6ABCB1CYP2D6HDAC4 | |
| Hydrochloric Acid SCHEMBL11025587 | 0.78 | HPGDS (0.52) | HPGDSCCR6ABCB1CYP2D6HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011044307-A1 | PHENYLOXADIAZOLE DERIVATIVES AS PGDS INHIBITORS | SANOFI-AVENTIS (FR) | 2011-04-14 | — | — | WO | disclosed |