Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.69 |
| ▸ | RARB | P10826 | 7/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | RARA | P10276 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 1/20 | 0.66 |
| ▸ | MTOR | P42345 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.52 |
| ▸ | RELA | Q04206 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.51 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27466500 | 0.99 | S1PR1 (0.71) | S1PR1RARBALDH1A1MEN1RARA | |
| Bromide SCHEMBL7339318 | 0.97 | S1PR1 (0.70) | S1PR1RARBALDH1A1MEN1RARA | |
| SCHEMBL290118 | 0.86 | RARB (0.89) | RARBALDH1A1MEN1RARAMAPT | |
| Cyclopropane SCHEMBL28261587 | 0.84 | RARB (0.81) | RARBALDH1A1MEN1RARAMAPT | |
| SCHEMBL970162 | 0.84 | RARB (0.90) | RARBALDH1A1MEN1RARAMAPT | |
| SCHEMBL18979307 | 0.84 | RARB (0.90) | RARBALDH1A1MEN1RARAMAPT | |
| SCHEMBL503506 | 0.84 | RARB (0.90) | RARBALDH1A1MEN1RARAMAPT | |
| Hydrochloric Acid SCHEMBL6557514 | 0.84 | RARB (0.86) | RARBALDH1A1MEN1RARAMAPT | |
| SCHEMBL503648 | 0.84 | RARB (0.90) | RARBALDH1A1MEN1RARAMAPT | |
| SCHEMBL270423 | 0.84 | RARB (0.90) | RARBALDH1A1MEN1RARAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8287969-B2 | Isosorbide derivatives and liquid crystal displays comprising the same | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2012-10-16 | — | — | US | disclosed |
| CN-102453037-A | Isosorbide derivative and liquid crystal display comprising the same | IND TECH RES INST | 2012-05-16 | — | — | CN | disclosed |
| US-20120086902-A1 | ISOSORBIDE DERIVATIVES AND LIQUID CRYSTAL DISPLAYS COMPRISING THE SAME | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2012-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120086902-A1 | ISOSORBIDE DERIVATIVES AND LIQUID CRYSTAL DISPLAYS COMPRISING THE SAME | CX3CR1, CBX3, YBX3 | S1PR1 3274/4885RARB 3012/4885ALDH1A1 2744/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.