Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 3/20 | 0.43 |
| ▸ | MAP4K1 | Q92918 | 3/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | IKBKB | O14920 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15045025 | 0.85 | MGAM (0.51) | MAPTALDH1A1GAANPC1MEN1 | |
| SCHEMBL20921201 | 0.84 | MEN1 (0.46) | KLKB1MAP4K1PTPN1ALDH1A1GAA | |
| SCHEMBL8007815 | 0.75 | NCK1 (0.55) | PTPN1ALDH1A1PIM1NPC1MEN1 | |
| SCHEMBL16093684 | 0.75 | BACE1 (0.55) | PTPN1ALDH1A1GAAPIM1KMT2A | |
| SCHEMBL31733680 | 0.75 | BACE1 (0.55) | PTPN1MAPTPIM1METAP2SCN9A | |
| SCHEMBL5625543 | 0.75 | GRM2 (0.47) | PTPN1MAPTPIM1METAP2SCN9A | |
| Hydrochloric Acid SCHEMBL31733671 | 0.73 | BACE1 (0.53) | PTPN1MAPTPIM1METAP2SCN9A | |
| SCHEMBL1668204 | 0.73 | TDP1 (0.46) | PTPN1MAPTALDH1A1GAAPIM1 | |
| SCHEMBL18077323 | 0.72 | SCN7A (0.46) | PTPN1MAPTALDH1A1GAAPIM1 | |
| SCHEMBL4986476 | 0.72 | PIM1 (0.42) | PTPN1MAPTALDH1A1GAAPIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2314586-A1 | 2-Acylaminothiazole derivative or salt thereof | Astellas Pharma Inc. (JP) | 2011-04-27 | — | — | EP | disclosed |