Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.55 |
| ▸ | GRM2 | Q14416 | 9/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | METAP2 | P50579 | 1/20 | 0.44 |
| ▸ | HSD17B14 | Q9BPX1 | 2/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL31733671 | 0.98 | BACE1 (0.53) | BACE1GRM2PTPN1METAP2HSD17B14 | |
| SCHEMBL5180091 | 0.84 | MGAM (0.56) | BACE1HSD17B14HDAC1HDAC2TSHR | |
| SCHEMBL16093684 | 0.79 | BACE1 (0.55) | BACE1GRM2PTPN1PIM1HDAC1 | |
| SCHEMBL8007815 | 0.79 | NCK1 (0.55) | BACE1GRM2PTPN1HSD17B14PIM1 | |
| SCHEMBL5625543 | 0.79 | GRM2 (0.47) | BACE1GRM2PTPN1METAP2PIM1 | |
| SCHEMBL14339761 | 0.78 | MAPT (0.48) | BACE1HDAC1HDAC2TSHRMAPT | |
| SCHEMBL27902504 | 0.78 | BACE1 (0.58) | BACE1PTPN1SCN7AKCNH2SCN9A | |
| SCHEMBL30387658 | 0.78 | BACE1 (0.58) | BACE1PTPN1SCN7AKCNH2SCN9A | |
| SCHEMBL1668204 | 0.77 | TDP1 (0.46) | PTPN1HSD17B14PIM1MAPT | |
| SCHEMBL4986476 | 0.76 | PIM1 (0.42) | GRM2PTPN1PIM1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025237891-A1 | QUINOLINE-2-CARBOXAMIDE DERIVATIVES AS RAD51 INHIBITORS FOR THE TREATMENT OF CANCER | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2025-11-20 | — | — | WO | claimed |
| WO-2025237891-A1 | QUINOLINE-2-CARBOXAMIDE DERIVATIVES AS RAD51 INHIBITORS FOR THE TREATMENT OF CANCER | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2025-11-20 | — | — | WO | disclosed |