Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 2/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.46 |
| ▸ | TACR1 | P25103 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | CCR5 | P51681 | 2/20 | 0.36 |
| ▸ | STS | P08842 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12801231 | 0.95 | OPRD1 (0.47) | OPRD1OPRK1TACR1TSHRALOX15 | |
| SCHEMBL1669035 | 0.94 | OPRD1 (0.39) | OPRD1OPRK1TACR1TSHRALOX15 | |
| SCHEMBL12800403 | 0.89 | OPRD1 (0.46) | OPRD1OPRK1TACR1TSHRALOX15 | |
| SCHEMBL1668756 | 0.89 | OPRD1 (0.48) | OPRD1OPRK1TACR1TSHRALOX15 | |
| SCHEMBL16498945 | 0.87 | OPRD1 (0.52) | OPRD1OPRK1TACR1TSHRALOX15 | |
| SCHEMBL1669123 | 0.86 | OPRD1 (0.51) | OPRD1OPRK1TACR1TSHRALOX15 | |
| SCHEMBL16499347 | 0.86 | OPRD1 (0.50) | OPRD1OPRK1TACR1TSHRALOX15 | |
| SCHEMBL16511721 | 0.85 | OPRD1 (0.45) | OPRD1OPRK1TACR1TSHRALOX15 | |
| SCHEMBL16499539 | 0.84 | OPRD1 (0.52) | OPRD1OPRK1TACR1TSHRALOX15 | |
| SCHEMBL12801195 | 0.84 | KDM4E (0.42) | OPRD1OPRK1TACR1TSHRALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011048409-A1 | CYCLIC AMINE DERIVATIVES HAVING BETA2 ADRENERGIC RECEPTOR AGONIST AND MUSCARINIC RECEPTOR ANTAGONIST ACTIVITY | ASTRAZENECA AB (SE) | 2011-04-28 | — | — | WO | disclosed |