Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 5/20 | 0.48 |
| ▸ | EHMT1 | Q9H9B1 | 4/20 | 0.48 |
| ▸ | QPCT | Q16769 | 3/20 | 0.47 |
| ▸ | AXL | P30530 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 4/20 | 0.46 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.45 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.45 |
| ▸ | HRH2 | P25021 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | RET | P07949 | 1/20 | 0.43 |
| ▸ | KIF5B | P33176 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29875845 | 0.95 | KDM4E (0.49) | EHMT2EHMT1QPCTAXLEGFR | |
| SCHEMBL17372611 | 0.88 | EHMT2 (0.60) | EHMT2EHMT1 | |
| SCHEMBL30764769 | 0.86 | EHMT2 (0.50) | EHMT2EHMT1AXLHRH3 | |
| SCHEMBL5103081 | 0.86 | EHMT2 (0.50) | EHMT2EHMT1AXLHRH3 | |
| SCHEMBL12521972 | 0.85 | EHMT2 (0.49) | EHMT2EHMT1AXL | |
| SCHEMBL12448367 | 0.84 | AXL (0.61) | AXLEGFRHRH3SRC | |
| SCHEMBL1930155 | 0.82 | EHMT2 (0.60) | EHMT2EHMT1 | |
| SCHEMBL12522390 | 0.82 | SPIN1 (0.48) | EHMT2EHMT1AXLHRH3 | |
| SCHEMBL3435110 | 0.82 | KDM4E (0.54) | HRH3 | |
| SCHEMBL4261231 | 0.81 | EHMT2 (0.59) | EHMT2EHMT1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011046970-A1 | AMINO - PYRIMIDINE COMPOUNDS AS INHIBITORS OF TBKL AND/OR IKK EPSILON | MYREXIS, INC. (US) | 2011-04-21 | — | — | WO | disclosed |