Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | EHMT2 | Q96KQ7 | 3/20 | 0.48 |
| ▸ | EHMT1 | Q9H9B1 | 3/20 | 0.48 |
| ▸ | QPCT | Q16769 | 2/20 | 0.47 |
| ▸ | AXL | P30530 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 4/20 | 0.46 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.45 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12801532 | 0.95 | EHMT2 (0.48) | EHMT2EHMT1QPCTAXLEGFR | |
| SCHEMBL1930155 | 0.88 | EHMT2 (0.60) | KDM4EGAAMAPTEHMT2EHMT1 | |
| SCHEMBL12448364 | 0.86 | KDM4E (0.51) | KDM4EGAAMAPTEHMT2EHMT1 | |
| SCHEMBL4261231 | 0.86 | EHMT2 (0.59) | KDM4EGAAMAPTEHMT2EHMT1 | |
| SCHEMBL1667163 | 0.84 | AXL (0.61) | KDM4EGAAMAPTQPCTAXL | |
| SCHEMBL17372611 | 0.82 | EHMT2 (0.60) | EHMT2EHMT1 | |
| SCHEMBL14393362 | 0.82 | HRH3 (0.60) | EHMT2QPCT | |
| SCHEMBL3435110 | 0.82 | KDM4E (0.54) | KDM4E | |
| SCHEMBL5103081 | 0.81 | EHMT2 (0.50) | KDM4EGAAMAPTEHMT2EHMT1 | |
| SCHEMBL30764769 | 0.81 | EHMT2 (0.50) | KDM4EGAAMAPTEHMT2EHMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114957127-B | Glutamine acyl cyclase inhibitor and preparation method and application thereof | 深圳大学 | 2023-08-15 | — | — | CN | disclosed |
| CN-114957127-A | Glutaminyl cyclase inhibitor and preparation method and application thereof | 深圳大学 | 2022-08-30 | — | — | CN | disclosed |