Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 8/20 | 0.58 |
| ▸ | DPP7 | Q9UHL4 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.39 |
| ▸ | LIPE | Q05469 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3311606 | 1.00 | DPP4 (0.58) | DPP4DPP7MEN1ALDH1A1KMT2A | |
| SCHEMBL25798260 | 1.00 | DPP4 (0.58) | DPP4DPP7MEN1ALDH1A1KMT2A | |
| SCHEMBL12801567 | 1.00 | DPP4 (0.58) | DPP4DPP7MEN1ALDH1A1KMT2A | |
| SCHEMBL3318472 | 0.88 | MEN1 (0.47) | DPP4DPP7MEN1ALDH1A1KMT2A | |
| SCHEMBL10311683 | 0.86 | DPP4 (0.60) | DPP4DPP7MEN1ALDH1A1KMT2A | |
| SCHEMBL738423 | 0.86 | DPP4 (0.60) | DPP4DPP7MEN1ALDH1A1KMT2A | |
| SCHEMBL10311720 | 0.86 | DPP4 (0.60) | DPP4DPP7MEN1ALDH1A1KMT2A | |
| SCHEMBL3313740 | 0.83 | CHRNB2 (0.42) | DPP4DPP7MEN1ALDH1A1KMT2A | |
| SCHEMBL14655996 | 0.82 | DPP4 (0.66) | DPP4DPP7MEN1ALDH1A1KMT2A | |
| SCHEMBL3311604 | 0.82 | MEN1 (0.41) | DPP4DPP7MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011046970-A1 | AMINO - PYRIMIDINE COMPOUNDS AS INHIBITORS OF TBKL AND/OR IKK EPSILON | MYREXIS, INC. (US) | 2011-04-21 | — | — | WO | disclosed |