Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK2D | Q13557 | 6/20 | 1.00 |
| ▸ | ABL1 | P00519 | 3/20 | 0.71 |
| ▸ | BCR | P11274 | 3/20 | 0.71 |
| ▸ | PRKCA | P17252 | 1/20 | 0.71 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.71 |
| ▸ | PLK1 | P53350 | 2/20 | 0.68 |
| ▸ | SRC | P12931 | 2/20 | 0.67 |
| ▸ | EGFR | P00533 | 1/20 | 0.67 |
| ▸ | PRKACA | P17612 | 1/20 | 0.67 |
| ▸ | PRKACG | P22612 | 1/20 | 0.67 |
| ▸ | PRKACB | P22694 | 1/20 | 0.67 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.64 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.63 |
| ▸ | NPC1 | O15118 | 2/20 | 0.63 |
| ▸ | RAB9A | P51151 | 2/20 | 0.63 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | CDK2 | P24941 | 3/20 | 0.58 |
| ▸ | CDK1 | P06493 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL823915 | 0.91 | CAMK2D (0.82) | CAMK2DABL1BCRPRKCAPRKCD | |
| SCHEMBL5732902 | 0.87 | CAMK2D (0.77) | CAMK2DABL1BCRPRKCAPRKCD | |
| SCHEMBL27444270 | 0.87 | PLK1 (0.78) | CAMK2DABL1BCRPRKCAPRKCD | |
| SCHEMBL2945644 | 0.85 | PLK1 (0.79) | CAMK2DABL1BCRPLK1SRC | |
| SCHEMBL12275705 | 0.85 | CAMK2D (0.73) | CAMK2DABL1BCRPRKCAPRKCD | |
| SCHEMBL3513778 | 0.84 | CAMK2D (0.73) | CAMK2DABL1BCRPRKCAPRKCD | |
| SCHEMBL12801287 | 0.84 | PLK1 (0.82) | CAMK2DABL1BCRPRKCAPRKCD | |
| SCHEMBL4386919 | 0.84 | ABL1 (0.82) | CAMK2DABL1BCRPRKCAPRKCD | |
| SCHEMBL14651462 | 0.84 | PLK1 (0.84) | CAMK2DABL1BCRPRKCAPRKCD | |
| SCHEMBL5733933 | 0.83 | CAMK2D (0.71) | CAMK2DABL1BCRPRKCAPRKCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011046970-A1 | AMINO - PYRIMIDINE COMPOUNDS AS INHIBITORS OF TBKL AND/OR IKK EPSILON | MYREXIS, INC. (US) | 2011-04-21 | — | — | WO | disclosed |