CAMK2D — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL224940	0.56	6/20
SCHEMBL232042	1.00	5/20
SCHEMBL234334	1.00	5/20
SCHEMBL147422	0.66	4/20
SCHEMBL144979	0.56	4/20
Tofacitinib (SCHEMBL322753)	1.00	3/20
SCHEMBL210190	0.74	3/20
SCHEMBL72322	0.73	3/20
SCHEMBL72323	0.73	3/20
SCHEMBL73871	0.70	3/20
SCHEMBL73872	0.70	3/20
SCHEMBL146734	0.67	3/20
SCHEMBL144651	0.67	3/20
SCHEMBL146677	0.67	3/20
SCHEMBL144378	0.66	3/20
SCHEMBL276090	0.66	3/20
SCHEMBL84772	0.65	3/20
SCHEMBL142020	0.65	3/20
SCHEMBL72298	0.64	3/20
SCHEMBL72299	0.64	3/20

Clinical trials — most relevant to CAMK2D by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
COMS for Chronic Ulcers Treatment	PHASE4	RECRUITING
The Efficacy of Computerized Cognitive Remediation Therapy for Chronic Schizophrenia	PHASE4	COMPLETED
Weight Loss Study: Genetics and Response to Naltrexone/Bupropion	PHASE4	RECRUITING
The G Protein-Coupled Receptor Kinase Type 2 Inhibitor Paroxetine as Adjunctive Therapy to Improve Insulin Sensitivity in Patients With Type 2 Diabetes Mellitus	PHASE3	UNKNOWN
Efficacy and Safety of Endoxifen in Bipolar I Disorder Patients	PHASE3	ACTIVE_NOT_RECRUITING
Evaluate Efficacy and Safety of Endoxifen in Bipolar I Disorder Patients	PHASE3	COMPLETED
The Phosphodiesterase 4 Inhibitor Roflumilast as an Adjunct to Antidepressants in Major Depressive Disorder Patients	PHASE1/PHASE2	WITHDRAWN
Anti-Estrogens - A Potential Treatment for Bipolar Affective Disorder in Women?	PHASE2	COMPLETED
Calcium Channel Blockade in Primary Aldosteronism	PHASE2	COMPLETED
Antidepressant Effects on cAMP Specific Phosphodiesterase (PDE4) in Depressed Patients	PHASE1	COMPLETED
Bioequivalence Study of Tacrolimus in Healthy Volunteers	PHASE1	COMPLETED
In Vivo Lithium Treatment Effects on Gene Expression Levels in Lymphoblastoid Cell Lines From Human Healthy Subjects	PHASE1	COMPLETED
Temsirolimus and Sorafenib in Advanced Hepatocellular Carcinoma	PHASE1	COMPLETED
The Safety and Efficacy Evaluation of Everolimus as an Adjunctive Treatment for Focal Refractory Epilepsy	EARLY_PHASE1	RECRUITING
Epithelioid Haemangioendothelioma Observational Study	nan	RECRUITING
NTRK 1,2,3 Rearrangements in Patients With Solid Tumors	nan	ACTIVE_NOT_RECRUITING
Multicenter Study of Patients With SHANK3 Mutations: Identification of Genes Modificators in Phelan-McDermid Syndrome (EUQ13)	nan	NOT_YET_RECRUITING
Calmodulin Gene Mutations in Patients With Ventricular Arrhythmia of Unknown Origin - A Screening Study	nan	WITHDRAWN
Abnormalities in the Effects of Insulin and Exercise on Glucose- and Lipid Metabolism in Obesity and Type 2 Diabetes	nan	COMPLETED
Influence of Pulse Electromagnetic Field Therapy on Myocardial Ischemia	nan	RECRUITING
Rapamycin as a Means of Interference With Reconsolidation of Posttraumatic Stress Disorder-related Traumatic Memory	nan	COMPLETED
Genetic Variants Associated With Adolescent Suicide Attempts	nan	COMPLETED
Diabetes Risk in London and Its Association with Vitamin D by Ethnic Group (DELVE)	nan	COMPLETED
Pompe & Pain - Study to Assess Nociceptive Pain in Adult Patients With Pompe Disease	nan	UNKNOWN
Evaluation of Vasopressin in the Vessels of Ovarian Neoplasms	nan	COMPLETED
Role of Nitric Oxide in Diabetic Patients With Erectile Dysfunction	nan	COMPLETED
Genes, Proteins, and Metabolites in Drug-resistant Epilepsy (DRE) Patients	nan	NOT_YET_RECRUITING
Urine Concentration of S100B in Extremely Premature Infants	nan	COMPLETED
Role of Amino Acids and Genetic Disorder in Pathogenesis of Heart Failure	nan	UNKNOWN
Relationship of Gestational Age and Urine Concentration of S100B in Preterm and Term Infants in the First Week of Life	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a CAMK2D binder may also engage these)

Protein	Name	Similarity
Q95266	—	1.000	Q95266 →
Q6PHZ2	—	1.000	Q6PHZ2 →
Q2HJF7	—	1.000	Q2HJF7 →
Q6DEH3	—	1.000	Q6DEH3 →
P11730	—	1.000	P11730 →
Q5ZKI0	—	1.000	Q5ZKI0 →
Q9DG02	—	1.000	Q9DG02 →
P08413	—	1.000	P08413 →
P11275	—	1.000	P11275 →
P15791	—	1.000	P15791 →
Q5RCC4	—	1.000	Q5RCC4 →
O77708	—	1.000	O77708 →
P11798	—	1.000	P11798 →
CAMK2A	Calcium/calmodulin-dependent protein kinase type II subunit alpha	1.000	landscape →
CAMK2G	Calcium/calmodulin-dependent protein kinase type II subunit gamma	1.000	landscape →
Q923T9	—	1.000	Q923T9 →
A8WXF6	—	1.000	A8WXF6 →
Q6DGS3	—	1.000	Q6DGS3 →
Q3MHJ9	—	0.998	Q3MHJ9 →
Q00168	—	0.998	Q00168 →
P28652	—	0.998	P28652 →
Q6PFQ0	—	0.995	Q6PFQ0 →
Q8RWL2	—	0.994	Q8RWL2 →
Q9M101	—	0.994	Q9M101 →
Q9FMP5	—	0.993	Q9FMP5 →
P13234	—	0.993	P13234 →
Q8VDF3	—	0.993	Q8VDF3 →
O49717	—	0.993	O49717 →
P10665	—	0.993	P10665 →
Q869W6	—	0.993	Q869W6 →