Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.42 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.42 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.42 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GAPDH | P04406 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13274190 | 1.00 | POLB (0.46) | POLBMEN1USP2KMT2AALDH1A1 | |
| SCHEMBL20691411 | 0.96 | POLB (0.47) | POLBMEN1USP2KMT2AALDH1A1 | |
| SCHEMBL18871302 | 0.90 | USP2 (0.55) | POLBMEN1USP2KMT2AALDH1A1 | |
| SCHEMBL21754836 | 0.90 | USP2 (0.55) | POLBMEN1USP2KMT2AALDH1A1 | |
| SCHEMBL25506254 | 0.90 | USP2 (0.55) | POLBMEN1USP2KMT2AALDH1A1 | |
| SCHEMBL15759263 | 0.90 | USP2 (0.55) | POLBMEN1USP2KMT2AALDH1A1 | |
| SCHEMBL21754881 | 0.90 | USP2 (0.55) | POLBMEN1USP2KMT2AALDH1A1 | |
| SCHEMBL12300564 | 0.90 | USP2 (0.55) | POLBMEN1USP2KMT2AALDH1A1 | |
| SCHEMBL12222446 | 0.90 | USP2 (0.55) | POLBMEN1USP2KMT2AALDH1A1 | |
| SCHEMBL13873368 | 0.90 | USP2 (0.55) | POLBMEN1USP2KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011039338-A2 | USE OF COMPOUNDS WITH SGLT-1/SGLT-2 INHIBITOR ACTIVITY FOR PRODUCING MEDICAMENTS FOR TREATMENT OF BONE DISEASES | SANOFI-AVENTIS (FR) | 2011-04-07 | — | — | WO | disclosed |