SCHEMBL18871302

SCHEMBL18871302

C[C@@H]1O[C@H](COC(=O)c2ccccc2)C(OC(=O)c2ccccc2)C1OC(=O)c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP2 O75604 2/20 0.55
POLB P06746 2/20 0.55
MEN1 O00255 1/20 0.55
KMT2A Q03164 1/20 0.55
PTPN1 P18031 4/20 0.50
ALDH1A1 P00352 1/20 0.49
CA1 P00915 2/20 0.47
CA2 P00918 2/20 0.47
TSHR P16473 1/20 0.47
CA9 Q16790 1/20 0.47
GAPDH P04406 2/20 0.46
F11 P03951 2/20 0.46
LGALS9 O00182 1/20 0.45
LGALS1 P09382 1/20 0.45
LGALS3 P17931 1/20 0.45
LGALS7; LGALS7B P47929 1/20 0.45
PTPN2 P17706 1/20 0.44
PTPN11 Q06124 1/20 0.44
ELANE P08246 1/20 0.44
HRAS P01112 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21754881 1.00 USP2 (0.55) USP2POLBMEN1KMT2APTPN1
SCHEMBL13873368 1.00 USP2 (0.55) USP2POLBMEN1KMT2APTPN1
SCHEMBL21754836 1.00 USP2 (0.55) USP2POLBMEN1KMT2APTPN1
SCHEMBL15759263 1.00 USP2 (0.55) USP2POLBMEN1KMT2APTPN1
SCHEMBL25506254 1.00 USP2 (0.55) USP2POLBMEN1KMT2APTPN1
SCHEMBL12300564 1.00 USP2 (0.55) USP2POLBMEN1KMT2APTPN1
SCHEMBL12222446 1.00 USP2 (0.55) USP2POLBMEN1KMT2APTPN1
SCHEMBL23895306 0.99 USP2 (0.54) USP2POLBMEN1KMT2APTPN1
SCHEMBL20739194 0.99 USP2 (0.54) USP2POLBMEN1KMT2APTPN1
SCHEMBL24378511 0.99 USP2 (0.54) USP2POLBMEN1KMT2APTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10286086-B2 Alternative nucleic acid molecules and uses thereof MODERNATX, INC. (US) 2019-05-14 US disclosed
US-20170136131-A1 ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF Modema Therapeutics, Inc. (US) 2017-05-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170136131-A1 ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF NSUN2, RNGTT, NSUN3 USP2 2981/4885POLB 37/4885MEN1 3388/4885
US-10286086-B2 Alternative nucleic acid molecules and uses thereof NSUN2, RNGTT, NSUN3 USP2 2981/4885POLB 37/4885MEN1 3388/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.