Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PLG | P00747 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | XIAP | P98170 | 2/20 | 0.30 |
| ▸ | BIRC3 | Q13489 | 2/20 | 0.30 |
| ▸ | BIRC2 | Q13490 | 2/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11984182 | 0.92 | ADRB3 (0.35) | F2F10PRSS1PLGADRB3 | |
| SCHEMBL11984046 | 0.92 | ADRB3 (0.35) | F2F10PRSS1PLGADRB3 | |
| SCHEMBL13059755 | 0.92 | F2 (0.36) | F2F10PRSS1PLGADRB3 | |
| SCHEMBL13818327 | 0.92 | F2 (0.36) | F2F10PRSS1PLGADRB3 | |
| SCHEMBL11984057 | 0.92 | F2 (0.36) | F2F10PRSS1PLGADRB3 | |
| SCHEMBL11984064 | 0.91 | F2 (0.36) | F2F10PRSS1PLGADRB3 | |
| SCHEMBL11984183 | 0.91 | ADRB3 (0.38) | F2F10PRSS1PLGADRB3 | |
| SCHEMBL12808401 | 0.91 | ADRB3 (0.36) | F2F10PRSS1ADRB3ADRA2B | |
| SCHEMBL11984181 | 0.90 | ADRB3 (0.36) | F2F10PRSS1ADRB3ADRA2B | |
| SCHEMBL8237405 | 0.90 | F2 (0.39) | F2F10PRSS1ADRB3ADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2305697-A2 | Macrocyclic inhibitors of Hepatitis C virus replication | Intermune, Inc. (US) | 2011-04-06 | — | — | EP | disclosed |