Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 1/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1403386 | 0.89 | SLC16A3 (0.55) | SLC16A3MCL1RECQLKMT2AMEN1 | |
| SCHEMBL1403387 | 0.89 | SLC16A3 (0.55) | SLC16A3MCL1RECQLKMT2AMEN1 | |
| SCHEMBL1403110 | 0.88 | KMT2A (0.50) | SLC16A3MCL1RECQLKMT2AMEN1 | |
| SCHEMBL1403108 | 0.88 | KMT2A (0.50) | SLC16A3MCL1RECQLKMT2AMEN1 | |
| SCHEMBL1403509 | 0.88 | KMT2A (0.51) | SLC16A3MCL1RECQLKMT2AMEN1 | |
| SCHEMBL1403508 | 0.88 | KMT2A (0.51) | SLC16A3MCL1RECQLKMT2AMEN1 | |
| SCHEMBL1403342 | 0.86 | HDAC8 (0.63) | SLC16A3MCL1RECQLKMT2AMEN1 | |
| SCHEMBL1403343 | 0.86 | HDAC8 (0.63) | SLC16A3MCL1RECQLKMT2AMEN1 | |
| SCHEMBL1866901 | 0.76 | HDAC8 (0.65) | LMNAALDH1A1MAPTHDAC8HDAC6 | |
| SCHEMBL1866899 | 0.76 | HDAC8 (0.65) | LMNAALDH1A1MAPTHDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2292593-A2 | Carbamic acid compounds comprising a sulfonamide linkage as HDAC inhibitors | TopoTarget UK Limited (GB) | 2011-03-09 | — | — | EP | disclosed |