SCHEMBL1866899

SCHEMBL1866899

CC(=O)/C=C/c1cccc2ccccc12

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC8 Q9BY41 1/20 0.65
HDAC6 Q9UBN7 1/20 0.65
MTNR1A P48039 1/20 0.63
MTNR1B P49286 1/20 0.63
MAPT P10636 3/20 0.59
LMNA P02545 2/20 0.59
SMN1; SMN2 Q16637 3/20 0.58
ALDH1A1 P00352 1/20 0.58
CYP1A1 P04798 1/20 0.58
CYP1A2 P05177 1/20 0.58
CYP2D6 P10635 1/20 0.58
HPGD P15428 1/20 0.58
NPY1R P25929 1/20 0.58
MAPK1 P28482 1/20 0.58
NPY2R P49146 1/20 0.58
CYP1B1 Q16678 1/20 0.58
IAPP P10997 1/20 0.56
KDM4E B2RXH2 2/20 0.54
NPC1 O15118 2/20 0.54
RAB9A P51151 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30257366 1.00 HDAC8 (0.65) HDAC8HDAC6MTNR1AMTNR1BMAPT
SCHEMBL1866901 1.00 HDAC8 (0.65) HDAC8HDAC6MTNR1AMTNR1BMAPT
SCHEMBL30963016 1.00 HDAC8 (0.65) HDAC8HDAC6MTNR1AMTNR1BMAPT
SCHEMBL3007219 0.85 HDAC8 (0.69) HDAC8HDAC6MTNR1AMTNR1BMAPT
SCHEMBL5598861 0.85 HDAC8 (0.69) HDAC8HDAC6MTNR1AMTNR1BMAPT
SCHEMBL23069115 0.83 HDAC8 (0.67) HDAC8HDAC6MTNR1AMTNR1BMAPT
SCHEMBL600540 0.83 HDAC8 (0.67) HDAC8HDAC6MTNR1AMTNR1BMAPT
SCHEMBL2903467 0.83 HDAC8 (0.67) HDAC8HDAC6MTNR1AMTNR1BMAPT
SCHEMBL79668 0.83 HDAC8 (0.67) HDAC8HDAC6MTNR1AMTNR1BMAPT
SCHEMBL29470165 0.83 HDAC8 (0.67) HDAC8HDAC6MTNR1AMTNR1BMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4242182-A OLEFINIC KETONES, OLEFINIC ACIDS, ESTERS AMIDES POPESCU FRANCINE 1980-12-30 US claimed
US-12519071-B2 Structure containing Sn layer or Sn alloy layer ISHIHARA CHEMICAL CO., LTD. (JP) 2026-01-06 US disclosed
EP-3238861-B1 SOLDER MATERIAL, SOLDER PASTE, FOAM SOLDER, FLUX COATING MATERIAL SENJU METAL INDUSTRY CO (JP) 2025-08-27 EP disclosed
US-12388035-B2 Structure comprising under barrier metal and solder layer, and method for producing structure ISHIHARA CHEMICAL CO., LTD. (JP) 2025-08-12 US disclosed
US-20240258255-A1 STRUCTURE COMPRISING UNDER BARRIER METAL AND SOLDER LAYER, AND METHOD FOR PRODUCING STRUCTURE ISHIHARA CHEMICAL CO., LTD. (JP) 2024-08-01 US disclosed
EP-4350748-A1 STRUCTURE COMPRISING UNDER BARRIER METAL AND SOLDER LAYER, AND METHOD FOR PRODUCING STRUCTURE Ishihara Chemical Co., Ltd (JP) 2024-04-10 EP disclosed
US-11939691-B2 Tin or tin alloy electroplating bath, and electronic component having electrodeposit formed thereon using the plating bath ISHIHARA CHEMICAL CO., LTD. (JP) 2024-03-26 US disclosed
US-11793823-B2 Compounds and pharmaceutical uses thereof SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) 2023-10-24 US disclosed
US-11793823-B2 Compounds and pharmaceutical uses thereof SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) 2023-10-24 US disclosed
CN-115836062-A Compound and medical application thereof 心悦生医股份有限公司 2023-03-21 CN disclosed
EP-0936213-A1 Unsaturated oxime ethers and their use as fungicides and insecticides ROHM AND HAAS COMPANY (US) 1999-08-18 EP disclosed
US-5858571-A TREATING A PULVERIZED HYDROGEN ABSORBING ALLOY WITH A SOLUTION COMPRISING A CONJUGATED UNSATURATED COMPOUND SHIN-ETSU CHEMICAL CO., LTD. (JP) 1999-01-12 US disclosed
EP-0872903-A1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder Shin-Etsu Chemical Co., Ltd. (JP) 1998-10-21 EP disclosed
EP-0124992-B1 HERBICIDAL CYCLOHEXANE-1,3-DIONE DERIVATIVES ICI AUSTRALIA LIMITED (AU) 1991-05-29 EP disclosed
EP-0172427-B1 PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER Shin-Etsu Chemical Co., Ltd. (JP) 1989-07-05 EP disclosed
US-4758639-A Process for production of vinyl polymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-19 US disclosed
US-4757124-A Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-12 US disclosed
US-4680400-A Herbicidal cyclohexane-1,3-dione-5-isoquinoline derivatives ICI AUSTRALIA LIMITED (AU) 1987-07-14 US disclosed
US-4640708-A Herbicidal cyclohexane-1,3-dione derivatives ICI AUSTRALIA LIMITED (AU) 1987-02-03 US disclosed
EP-0124992-A1 Herbicidal cyclohexane-1,3-dione derivatives ICI AUSTRALIA LIMITED (AU) 1984-11-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11793823-B2 Compounds and pharmaceutical uses thereof HRH4, OR10J3, CYP3A5 HDAC8 1674/4885HDAC6 609/4885MTNR1A 1717/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.