Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13472620 | 0.87 | ALDH1A1 (0.68) | ALDH1A1L3MBTL1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL26999887 | 0.86 | ALDH1A1 (0.66) | ALDH1A1L3MBTL1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL8470821 | 0.84 | ALDH1A1 (0.68) | ALDH1A1L3MBTL1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL10206069 | 0.82 | ALDH1A1 (0.69) | ALDH1A1L3MBTL1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL1831560 | 0.82 | ALDH1A1 (0.69) | ALDH1A1L3MBTL1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL14509630 | 0.82 | ALDH1A1 (0.69) | ALDH1A1L3MBTL1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL16495170 | 0.82 | ALDH1A1 (0.69) | ALDH1A1L3MBTL1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL13853654 | 0.79 | ALDH1A1 (0.75) | ALDH1A1L3MBTL1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL13853692 | 0.79 | ALDH1A1 (0.75) | ALDH1A1L3MBTL1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL12788564 | 0.78 | ALDH1A1 (0.64) | ALDH1A1L3MBTL1HTTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2292613-A1 | DIHYDROINDOLINONE DERIVATIVES | Shanghai Institute of Pharmaceutical Industry (CN) | 2011-03-09 | — | — | EP | disclosed |