Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 2/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | NQO2 | P16083 | 2/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL561626 | 0.85 | GPR35 (0.47) | LCKPDE4DMAPK1GPR35MAPT | |
| SCHEMBL561388 | 0.84 | RXFP1 (0.40) | LCKPDE4DMAPK1GPR35MAPT | |
| SCHEMBL561469 | 0.84 | PDE4D (0.45) | LCKPDE4DMAPK1MAPTNQO2 | |
| SCHEMBL562408 | 0.84 | GRM2 (0.41) | LCKPDE4DMAPK1GPR35MAPT | |
| SCHEMBL13074496 | 0.84 | PDE4D (0.42) | LCKPDE4DMAPK1GPR35MAPT | |
| SCHEMBL561666 | 0.81 | PDE10A (0.47) | LCKPDE4DMAPK1MAPTPTGER4 | |
| SCHEMBL8292463 | 0.78 | LCK (0.42) | LCKMAPK1MAPTNQO2PTGER4 | |
| SCHEMBL561634 | 0.75 | LCK (0.38) | LCKPDE4DMAPK1GPR35MAPT | |
| SCHEMBL6080299 | 0.75 | CNR2 (0.42) | LCKPDE4DMAPK1GPR35MAPT | |
| SCHEMBL10015177 | 0.74 | LCK (0.41) | LCKMAPK1MAPTNQO2GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1673385-B1 | MACROCYCLIC PEPTIDES ACTIVE AGAINST THE HEPATITIS C VIRUS | BOEHRINGER INGELHEIM INT (DE) | 2011-03-02 | — | — | EP | disclosed |