Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 15/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11929409 | 0.94 | CTSK (0.50) | CTSK | |
| SCHEMBL1401076 | 0.88 | CTSK (0.41) | CTSKCTSSTDP1MEN1LMNA | |
| SCHEMBL1401074 | 0.88 | CTSK (0.41) | CTSKCTSSTDP1MEN1LMNA | |
| SCHEMBL10266406 | 0.87 | CTSK (0.40) | CTSKCTSSMEN1LMNATSHR | |
| SCHEMBL11929410 | 0.79 | CTSK (0.51) | CTSKCTSS | |
| SCHEMBL29679376 | 0.77 | CTSK (0.54) | CTSK | |
| SCHEMBL2546240 | 0.75 | CTSK (0.48) | CTSKCTSS | |
| SCHEMBL5468267 | 0.75 | CTSK (0.48) | CTSKCTSS | |
| SCHEMBL1401046 | 0.74 | CTSK (0.46) | CTSKCTSSMEN1LMNATSHR | |
| SCHEMBL1401049 | 0.74 | CTSK (0.46) | CTSKCTSSMEN1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1417975-B1 | REMEDIES FOR DISEASES WITH BONE MASS LOSS HAVING EP4 AGONIST AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO (JP) | 2011-03-02 | — | — | EP | disclosed |