Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 15/20 | 0.59 |
| ▸ | DPP8 | Q6V1X1 | 5/20 | 0.46 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.42 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1408411 | 0.87 | DPP4 (0.62) | DPP4DPP8DPP9ALPLPLA2G2A | |
| SCHEMBL1407325 | 0.87 | DPP4 (0.59) | DPP4DPP8DPP9ALPLPLA2G2A | |
| SCHEMBL1407673 | 0.81 | DPP4 (0.66) | DPP4DPP8DPP9ALPL | |
| SCHEMBL21981605 | 0.77 | DPP4 (0.51) | DPP4ALPL | |
| SCHEMBL1408214 | 0.76 | DPP4 (0.63) | DPP4DPP8DPP9PLA2G2A | |
| SCHEMBL1408016 | 0.74 | DPP4 (1.00) | DPP4DPP8DPP9 | |
| SCHEMBL1407844 | 0.71 | DPP4 (0.75) | DPP4DPP8DPP9 | |
| SCHEMBL12809829 | 0.69 | DPP4 (0.67) | DPP4DPP8DPP9 | |
| SCHEMBL28435242 | 0.68 | MAPT (0.52) | DPP4DPP8DPP9ALPLPLA2G2A | |
| SCHEMBL2704427 | 0.67 | PLA2G2A (0.44) | DPP4DPP8DPP9ALPLPLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1836206-B1 | AZOLOPYRIMIDINE-BASED INHIBITORS OF DIPEPTIDYL PEPTIDASE IV AND METHODS | BRISTOL MYERS SQUIBB CO (US) | 2011-03-09 | — | — | EP | disclosed |