Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | NQO1 | P15559 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.34 |
| ▸ | HNF4A | P41235 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.33 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12809944 | 0.82 | TRPM4 (0.37) | MAPTALDH1A1NPSR1SMN1; SMN2HIF1A | |
| SCHEMBL1408900 | 0.71 | MAPT (0.39) | MAPTALDH1A1NPSR1NQO1TP53 | |
| SCHEMBL1408342 | 0.66 | MAPT (0.37) | MAPTALDH1A1NPSR1NQO1TP53 | |
| SCHEMBL12809939 | 0.63 | TRPM4 (0.37) | MAPTALDH1A1NPSR1SMN1; SMN2HIF1A | |
| SCHEMBL12647693 | 0.63 | KDM4E (0.43) | MAPTALDH1A1NPSR1NQO1SMN1; SMN2 | |
| SCHEMBL1408738 | 0.63 | MEN1 (0.39) | MAPTALDH1A1NPSR1NQO1TDP1 | |
| SCHEMBL12809653 | 0.62 | ALDH1A1 (0.53) | MAPTALDH1A1NPSR1NQO1 | |
| SCHEMBL17065823 | 0.62 | NPSR1 (0.44) | MAPTALDH1A1NPSR1NQO1CYP1A2 | |
| SCHEMBL9040694 | 0.62 | ALDH1A1 (0.60) | MAPTALDH1A1NPSR1NQO1TP53 | |
| SCHEMBL1128095 | 0.61 | NQO1 (0.56) | MAPTALDH1A1NPSR1NQO1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2295503-A1 | Dibenzorhodamine dyes useful as fluorescent labelling agents | Applera Corporation (US) | 2011-03-16 | — | — | EP | disclosed |
| US-7833756-B2 | Methods of labelling polynucleotides with dibenzorhodamine dyes | APPLIED BIOSYSTEMS, LLC (US) | 2010-11-16 | — | — | US | disclosed |
| EP-2221347-A1 | Sulfonated diarylrhodamine dyes | Applera Corporation (US) | 2010-08-25 | — | — | EP | disclosed |
| EP-2179996-A1 | Sulfonated diarylrhodamine dyes | Applera Corporation (US) | 2010-04-28 | — | — | EP | disclosed |