Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | CLK1 | P49759 | 2/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL888948 | 0.87 | INSR (0.36) | SMN1; SMN2MAPTMEN1KMT2ARAB9A | |
| SCHEMBL12810233 | 0.83 | PTGS1 (0.51) | SMN1; SMN2MAPTLDHAKDM4EMEN1 | |
| SCHEMBL12810133 | 0.77 | PTGS1 (0.48) | SMN1; SMN2MAPTMEN1KMT2ARAB9A | |
| SCHEMBL27936386 | 0.74 | SMN1; SMN2 (0.53) | SMN1; SMN2MAPTLDHAKDM4EMEN1 | |
| SCHEMBL12810095 | 0.72 | SMN1; SMN2 (0.47) | SMN1; SMN2MAPTLDHAKDM4EMEN1 | |
| SCHEMBL29882188 | 0.72 | SMN1; SMN2 (0.50) | SMN1; SMN2MAPTLDHAKDM4EMEN1 | |
| SCHEMBL28820698 | 0.72 | SMN1; SMN2 (0.50) | SMN1; SMN2MAPTLDHAKDM4EMEN1 | |
| SCHEMBL6268298 | 0.71 | SMN1; SMN2 (0.49) | SMN1; SMN2MAPTLDHAKDM4EMEN1 | |
| SCHEMBL6268297 | 0.71 | SMN1; SMN2 (0.49) | SMN1; SMN2MAPTLDHAKDM4EMEN1 | |
| SCHEMBL30224526 | 0.70 | SMN1; SMN2 (0.56) | SMN1; SMN2MAPTLDHAKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110064697-A1 | HEPATITIS C VIRUS INHIBITORS | ENANTA PHARMACEUTICALS, INC. | 2011-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110064697-A1 | HEPATITIS C VIRUS INHIBITORS | HAVCR2, EIF2AK2, SLC10A1 | SMN1; SMN2 4269/4885MAPT 4286/4885LDHA 1441/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.