SCHEMBL12810099

SCHEMBL12810099

C=CC(=O)C[C@H](CC)CC(C)(C)[Si](C)(C)O

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.36
ALDH1A1 P00352 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12809953 0.81
SCHEMBL12183847 0.81
SCHEMBL6762053 0.78 TSHR (0.52) TSHRALDH1A1
SCHEMBL15752240 0.77
SCHEMBL14818215 0.76
SCHEMBL12714994 0.72 TSHR (0.37) TSHRALDH1A1
SCHEMBL19278313 0.71 ALDH1A1 (0.31) ALDH1A1
SCHEMBL14928073 0.69 TSHR (0.48) TSHRALDH1A1
SCHEMBL8680099 0.68 TSHR (0.57) TSHRALDH1A1
SCHEMBL15752256 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1578733-B1 PROCESS FOR THE PREPARATION OF ROSUVASTATIN RANBAXY LAB LTD (IN) 2011-03-09 EP disclosed