Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | HTT | P42858 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | STAT3 | P40763 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | APP | P05067 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | NR2F2 | P24468 | 3/20 | 0.45 |
| ▸ | GALR3 | O60755 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12811751 | 0.89 | MAPT (0.51) | MAPTHTTTSHRLMNAPOLB | |
| SCHEMBL12788045 | 0.87 | NPC1 (0.48) | MAPTHTTTSHRLMNAPOLB | |
| SCHEMBL12788042 | 0.86 | MAPT (0.47) | MAPTHTTTSHRLMNAPOLB | |
| SCHEMBL12811456 | 0.83 | KDM4E (0.42) | HTTTSHRLMNAPOLBSMN1; SMN2 | |
| SCHEMBL12788003 | 0.81 | SMN1; SMN2 (0.54) | MAPTHTTTSHRLMNAPOLB | |
| SCHEMBL12788866 | 0.81 | MAPT (0.48) | MAPTHTTTSHRLMNAPOLB | |
| SCHEMBL12788071 | 0.80 | NPC1 (0.48) | MAPTHTTTSHRLMNAPOLB | |
| SCHEMBL12788054 | 0.80 | MAPT (0.48) | MAPTHTTTSHRLMNAPOLB | |
| SCHEMBL12788920 | 0.80 | MAPT (0.57) | MAPTHTTTSHRLMNAPOLB | |
| SCHEMBL12788745 | 0.79 | MAPT (0.47) | MAPTHTTTSHRLMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011025505-A1 | PTERIDINES AND THEIR USE AS AGROCHEMICALS | DOW AGROSCIENCES LLC (US) | 2011-03-03 | — | — | WO | disclosed |