Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | HTT | P42858 | 4/20 | 0.54 |
| ▸ | TSHR | P16473 | 4/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | STAT3 | P40763 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | TDP2 | O95551 | 1/20 | 0.48 |
| ▸ | NSD2 | O96028 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | NR2F2 | P24468 | 3/20 | 0.48 |
| ▸ | GALR3 | O60755 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12788911 | 0.91 | MAPT (0.44) | SMN1; SMN2MAPTHTTTSHRHSD17B10 | |
| SCHEMBL12788763 | 0.88 | MAPT (0.47) | SMN1; SMN2MAPTHTTTSHRHSD17B10 | |
| SCHEMBL12788920 | 0.87 | MAPT (0.57) | SMN1; SMN2MAPTHTTTSHRHSD17B10 | |
| SCHEMBL12788727 | 0.86 | HTT (0.40) | SMN1; SMN2MAPTHTTTSHRHSD17B10 | |
| SCHEMBL12788887 | 0.85 | MAPT (0.53) | SMN1; SMN2MAPTHTTTSHRHSD17B10 | |
| SCHEMBL12788731 | 0.85 | MAPT (0.53) | SMN1; SMN2MAPTHTTTSHRHSD17B10 | |
| SCHEMBL12788608 | 0.85 | MAPT (0.53) | SMN1; SMN2MAPTHTTTSHRHSD17B10 | |
| SCHEMBL12788972 | 0.83 | RAB9A (0.43) | SMN1; SMN2MAPTHTTTSHRHSD17B10 | |
| SCHEMBL12788891 | 0.83 | HTT (0.44) | SMN1; SMN2MAPTHTTTSHRHSD17B10 | |
| SCHEMBL12788740 | 0.83 | HTT (0.43) | SMN1; SMN2MAPTHTTTSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8895568-B2 | Compositions comprising substituted pteridines as agrochemicals | DOW AGROSCIENCES, LLC. (US) | 2014-11-25 | — | — | US | disclosed |
| US-8895568-B2 | Compositions comprising substituted pteridines as agrochemicals | DOW AGROSCIENCES, LLC. (US) | 2014-11-25 | — | — | US | disclosed |
| US-20130252960-A1 | PTERIDINES AND THEIR USE AS AGROCHEMICALS | DOW AGROSCIENCES LLC (US) | 2013-09-26 | — | — | US | disclosed |
| US-20130252960-A1 | PTERIDINES AND THEIR USE AS AGROCHEMICALS | DOW AGROSCIENCES LLC (US) | 2013-09-26 | — | — | US | disclosed |
| US-8461164-B2 | Pteridines and their use as agrochemicals | DOW AGROSCIENCES, LLC. (US) | 2013-06-11 | — | — | US | disclosed |
| US-8461164-B2 | Pteridines and their use as agrochemicals | DOW AGROSCIENCES, LLC. (US) | 2013-06-11 | — | — | US | disclosed |
| US-20110054173-A1 | PTERIDINES AND THEIR USE AS AGROCHEMICALS | DOW AGROSCIENCES LLC (US) | 2011-03-03 | — | — | US | disclosed |
| US-20110054173-A1 | PTERIDINES AND THEIR USE AS AGROCHEMICALS | DOW AGROSCIENCES LLC (US) | 2011-03-03 | — | — | US | disclosed |
| WO-2011025505-A1 | PTERIDINES AND THEIR USE AS AGROCHEMICALS | DOW AGROSCIENCES LLC (US) | 2011-03-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130252960-A1 | PTERIDINES AND THEIR USE AS AGROCHEMICALS | CBR3, CBR1, AKR1C4 | SMN1; SMN2 4036/4885MAPT 4788/4885HTT 2437/4885 |
| US-20110054173-A1 | PTERIDINES AND THEIR USE AS AGROCHEMICALS | PIR, PFAS, PNPO | SMN1; SMN2 2818/4885MAPT 3907/4885HTT 1265/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.