Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | WNT3A | P56704 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 3/20 | 0.46 |
| ▸ | DRD2 | P14416 | 3/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1443467 | 0.94 | KMT2A (0.54) | KMT2AMEN1ALDH1A1MAPTKDM4E | |
| SCHEMBL1443167 | 0.91 | KMT2A (0.55) | KMT2AMEN1ALDH1A1MAPTKDM4E | |
| SCHEMBL12812507 | 0.91 | NPC1 (0.52) | KMT2AMEN1ALDH1A1MAPTKDM4E | |
| SCHEMBL1442495 | 0.90 | HTR1A (0.52) | KMT2AMEN1ALDH1A1MAPTKDM4E | |
| SCHEMBL12812509 | 0.89 | MEN1 (0.50) | KMT2AMEN1ALDH1A1MAPTKDM4E | |
| SCHEMBL1442357 | 0.89 | KMT2A (0.59) | KMT2AMEN1ALDH1A1MAPTKDM4E | |
| SCHEMBL13276353 | 0.89 | KMT2A (0.52) | KMT2AMEN1ALDH1A1MAPTKDM4E | |
| SCHEMBL1443409 | 0.88 | MAPT (0.56) | KMT2AMEN1ALDH1A1MAPTKDM4E | |
| SCHEMBL1443398 | 0.88 | HTR1A (0.54) | KMT2AMEN1ALDH1A1MAPTKDM4E | |
| SCHEMBL1442104 | 0.87 | SMN1; SMN2 (0.59) | KMT2AMEN1ALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011026579-A1 | SUBSTITUTED AMINOQUINOXALINES AS TYROSINE THREONINE KINASE INHIBITORS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2011-03-10 | — | — | WO | disclosed |