Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F9 | P00740 | 12/20 | 0.48 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12812955 | 0.92 | F9 (0.50) | F9 | |
| SCHEMBL1438630 | 0.91 | F9 (0.51) | F9 | |
| SCHEMBL1439994 | 0.91 | F9 (0.46) | F9ROCK2 | |
| SCHEMBL1438388 | 0.91 | F9 (0.46) | F9ROCK2 | |
| SCHEMBL1441109 | 0.89 | F9 (0.52) | F9 | |
| SCHEMBL15104435 | 0.87 | F9 (0.46) | F9 | |
| SCHEMBL1440213 | 0.87 | F9 (0.46) | F9 | |
| SCHEMBL12812948 | 0.87 | F9 (0.52) | F9ROCK2 | |
| SCHEMBL1439372 | 0.87 | F9 (0.51) | F9 | |
| SCHEMBL1438640 | 0.86 | F9 (0.50) | F9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011025565-A1 | MORPHOLINONE COMPOUNDS AS FACTOR IXA INHIBITORS | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2011-03-03 | — | — | WO | disclosed |