Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.73 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.49 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | BRAF | P15056 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL418439 | 0.84 | KMO (1.00) | KMOHDAC8HDAC4HDAC2SERPINE1 | |
| SCHEMBL9338681 | 0.83 | KMO (0.73) | KMOHDAC8HDAC4HDAC2SERPINE1 | |
| SCHEMBL6051833 | 0.82 | KMO (0.96) | KMOHDAC8HDAC4HDAC2SERPINE1 | |
| SCHEMBL29875686 | 0.81 | KMO (0.76) | KMOHDAC8HDAC4HDAC2SERPINE1 | |
| SCHEMBL11695796 | 0.81 | KMO (0.71) | KMOHDAC8HDAC4HDAC2SERPINE1 | |
| SCHEMBL19862476 | 0.81 | KMO (0.70) | KMOHDAC8HDAC4HDAC2SERPINE1 | |
| SCHEMBL28149501 | 0.80 | KMO (0.69) | KMOHDAC8HDAC4HDAC2SERPINE1 | |
| SCHEMBL8195584 | 0.80 | KMO (0.69) | KMOHDAC8HDAC4HDAC2SERPINE1 | |
| Hydrogen Peroxide SCHEMBL11391460 | 0.79 | KMO (0.71) | KMOHDAC8HDAC4HDAC2SERPINE1 | |
| SCHEMBL12814292 | 0.79 | KMO (0.67) | KMOHDAC8HDAC4HDAC2SERPINE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2699606-B1 | POLYMERS FUNCTIONALIZED WITH A CARBOXYLIC OR THIOCARBOXYLIC ESTER CONTAINING A SILYLATED AMINO GROUP | BRIDGESTONE CORP (JP) | 2016-09-28 | — | — | EP | claimed |
| EP-2699606-A2 | POLYMERS FUNCTIONALIZED WITH A CARBOXYLIC OR THIOCARBOXYLIC ESTER CONTAINING A SILYLATED AMINO GROUP | Bridgestone Corporation (JP) | 2014-02-26 | — | — | EP | claimed |
| US-20140018500-A1 | Polymers Functionalized With A Carboxylic Or Thiocarboxylic Ester Containing A Silylated Amino Group | BRIDGESTONE CORPORATION (JP) | 2014-01-16 | — | — | US | claimed |
| WO-2012135451-A2 | POLYMERS FUNCTIONALIZED WITH A CARBOXYLIC OR THIOCARBOXYLIC ESTER CONTAINING A SILYLATED AMINO GROUP | BRIDGESTONE CORPORATION (JP) | 2012-10-04 | — | — | WO | claimed |
| EP-2699606-B1 | POLYMERS FUNCTIONALIZED WITH A CARBOXYLIC OR THIOCARBOXYLIC ESTER CONTAINING A SILYLATED AMINO GROUP | BRIDGESTONE CORP (JP) | 2016-09-28 | — | — | EP | disclosed |
| US-9403919-B2 | Polymers functionalized with a carboxylic or thiocarboxylic ester containing a silylated amino group | BRIDGESTONE CORPORATION (JP) | 2016-08-02 | — | — | US | disclosed |
| EP-2699606-A2 | POLYMERS FUNCTIONALIZED WITH A CARBOXYLIC OR THIOCARBOXYLIC ESTER CONTAINING A SILYLATED AMINO GROUP | Bridgestone Corporation (JP) | 2014-02-26 | — | — | EP | disclosed |
| US-20140018500-A1 | Polymers Functionalized With A Carboxylic Or Thiocarboxylic Ester Containing A Silylated Amino Group | BRIDGESTONE CORPORATION (JP) | 2014-01-16 | — | — | US | disclosed |
| WO-2012135451-A2 | POLYMERS FUNCTIONALIZED WITH A CARBOXYLIC OR THIOCARBOXYLIC ESTER CONTAINING A SILYLATED AMINO GROUP | BRIDGESTONE CORPORATION (JP) | 2012-10-04 | — | — | WO | disclosed |