Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.45 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | HSD17B3 | P37058 | 6/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27984671 | 1.00 | GSK3B (0.57) | GSK3BFFAR1PLA2G2APLA2G5CA2 | |
| SCHEMBL23330896 | 0.86 | GSK3B (0.65) | GSK3BHSD17B3HTTMEN1ALDH1A1 | |
| SCHEMBL20504178 | 0.86 | PLA2G2A (0.44) | GSK3BFFAR1PLA2G2APLA2G5CA2 | |
| SCHEMBL23300728 | 0.81 | GSK3B (0.54) | GSK3BHTTMEN1ALDH1A1MAPT | |
| SCHEMBL13919889 | 0.79 | GSK3B (0.69) | GSK3BHTTMEN1ALDH1A1MAPT | |
| SCHEMBL24722219 | 0.79 | GSK3B (0.51) | GSK3BHTTMEN1ALDH1A1MAPT | |
| SCHEMBL24722218 | 0.79 | GSK3B (0.51) | GSK3BHTTMEN1ALDH1A1MAPT | |
| SCHEMBL16938961 | 0.79 | PLA2G2A (0.41) | FFAR1PLA2G2APLA2G5CA2HSD17B3 | |
| SCHEMBL17181083 | 0.79 | PLA2G2A (0.41) | FFAR1PLA2G2APLA2G5CA2HSD17B3 | |
| SCHEMBL17190866 | 0.79 | PLA2G2A (0.41) | FFAR1PLA2G2APLA2G5CA2HSD17B3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012131084-A1 | TRIARYL- AND TRIHETEROARYL- BENZENE MONOMERS AND POLYMERS | IMPERIAL INNOVATIONS LIMITED (GB) | 2012-10-04 | — | — | WO | disclosed |