Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 4/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.30 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12821890 | 0.95 | ACHE (0.39) | SMN1; SMN2NPC1RAB9ATSHRHPGD | |
| SCHEMBL12816500 | 0.93 | MAPT (0.33) | SMN1; SMN2NPC1RAB9ATSHRHPGD | |
| SCHEMBL12817110 | 0.93 | MAPT (0.33) | SMN1; SMN2NPC1RAB9ATSHRHPGD | |
| SCHEMBL12817375 | 0.90 | ACHE (0.46) | SMN1; SMN2NPC1RAB9ATSHRHPGD | |
| SCHEMBL12815351 | 0.88 | HPGD (0.38) | SMN1; SMN2NPC1RAB9ATSHRHPGD | |
| SCHEMBL10318440 | 0.88 | ACHE (0.46) | SMN1; SMN2NPC1RAB9ATSHRHPGD | |
| SCHEMBL12814561 | 0.88 | ACHE (0.46) | SMN1; SMN2NPC1RAB9ATSHRHPGD | |
| SCHEMBL12817554 | 0.86 | ACHE (0.36) | ACHE | |
| SCHEMBL12817423 | 0.86 | ACHE (0.36) | ACHE | |
| SCHEMBL12817609 | 0.86 | ESR1 (0.35) | ACHEMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012133929-A1 | METHOD FOR PRODUCING THE TRANSITION METAL ION COMPLEX, CATALYST FOR TRIMERIZATION, AND METHOD FOR PRODUCING 1-HEXENE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-10-04 | — | — | WO | disclosed |