SCHEMBL12817455

SCHEMBL12817455

CC1=C(C)C(C)C([Si](c2ccccc2)(c2cccc(C)c2)c2cc(C)cc([Si](C)(C)C)c2)=C1C

nearest known ligand 0.30

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.30
HPGD P15428 1/20 0.30
TSHR P16473 1/20 0.30
RAB9A P51151 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12816364 0.96
SCHEMBL12816460 0.95
SCHEMBL12816790 0.95
SCHEMBL12818048 0.92 ACHE (0.34)
SCHEMBL12816593 0.91
SCHEMBL12818209 0.91 ESR1 (0.30)
SCHEMBL15410076 0.91 ESR1 (0.30)
SCHEMBL12814804 0.91 ACHE (0.33) NPC1HPGDTSHRRAB9ASMN1; SMN2
SCHEMBL10318699 0.91 ACHE (0.33) NPC1HPGDTSHRRAB9ASMN1; SMN2
SCHEMBL15409369 0.89

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012133929-A1 METHOD FOR PRODUCING THE TRANSITION METAL ION COMPLEX, CATALYST FOR TRIMERIZATION, AND METHOD FOR PRODUCING 1-HEXENE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-04 WO disclosed