Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL712012 | 1.00 | HSD17B10 (0.37) | HSD17B10TDP1MEN1THRBHTT | |
| SCHEMBL17262666 | 1.00 | HSD17B10 (0.37) | HSD17B10TDP1MEN1THRBHTT | |
| SCHEMBL1274341 | 1.00 | HSD17B10 (0.37) | HSD17B10TDP1MEN1THRBHTT | |
| SCHEMBL1342489 | 0.97 | — | — | |
| SCHEMBL10766116 | 0.90 | TSHR (0.36) | HSD17B10MEN1THRBHTTKMT2A | |
| SCHEMBL1274298 | 0.90 | HTT (0.39) | HSD17B10MEN1THRBHTTKMT2A | |
| SCHEMBL6659201 | 0.88 | HTT (0.42) | HSD17B10TDP1MEN1THRBHTT | |
| SCHEMBL5178951 | 0.88 | HTT (0.42) | HSD17B10TDP1MEN1THRBHTT | |
| SCHEMBL17262664 | 0.88 | HTT (0.42) | HSD17B10TDP1MEN1THRBHTT | |
| SCHEMBL2410543 | 0.85 | HTT (0.37) | HSD17B10MEN1THRBHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024086501-A1 | DELIVERY PARTICLES BASED ON AMINE-THIOL-ENE CONJUGATES AND DERIVATIVES | ENCAPSYS, LLC (US) | 2024-04-25 | — | — | WO | disclosed |
| EP-2879675-A1 | COMPOUNDS AND METHODS FOR TARGETING HSP90 | Duke University (US) | 2015-06-10 | — | — | EP | disclosed |
| WO-2014025395-A1 | COMPOUNDS AND METHODS FOR TARGETING HSP90 | DUKE UNIVERSITY (US) | 2014-02-13 | — | — | WO | disclosed |
| EP-2691403-A1 | NEW BORANOPHOSPHATE ANALOGUES OF CYCLIC NUCLEOTIDES | BIOLOG Life Science Institute Forschungslabor Und Biochemica-Vertrieb GmbH (DE) | 2014-02-05 | — | — | EP | disclosed |
| WO-2012130829-A1 | NEW BORANOPHOSPHATE ANALOGUES OF CYCLIC NUCLEOTIDES | BIOLOG LIFE SCIENCE INSTITUTE FORSCHUNGSLABOR UND BIOCHEMICA-VERTRIEB GMBH (DE) | 2012-10-04 | — | — | WO | disclosed |