Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.33 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5178951 | 1.00 | HTT (0.42) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL17262664 | 1.00 | HTT (0.42) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL1274298 | 0.98 | HTT (0.39) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL10766116 | 0.93 | TSHR (0.36) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL1342489 | 0.91 | — | — | |
| SCHEMBL1274341 | 0.88 | HSD17B10 (0.37) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL712012 | 0.88 | HSD17B10 (0.37) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL12818985 | 0.88 | HSD17B10 (0.37) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL17262666 | 0.88 | HSD17B10 (0.37) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL7745536 | 0.86 | HTT (0.40) | HTTMEN1THRBKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004003050-A1 | POLYETHER URETHANE AMINES | HUNTSMAN ADVANCED MATERIALS (SWITZERLAND) GMBH (CH) | 2004-01-08 | — | — | WO | disclosed |