Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 3/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | P2RY1 | P47900 | 3/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12819938 | 0.78 | P2RY1 (0.46) | DRD1P2RY1 | |
| SCHEMBL12303715 | 0.77 | P2RY1 (0.43) | DRD1KCNH2P2RY1 | |
| SCHEMBL12303747 | 0.77 | TDP1 (0.54) | P2RY1 | |
| SCHEMBL12303705 | 0.77 | MAPK10 (0.45) | P2RY1 | |
| SCHEMBL12303718 | 0.76 | TRPV1 (0.44) | DRD1KCNH2ALDH1A1MAPTATM | |
| SCHEMBL12303727 | 0.72 | P2RY1 (0.49) | DRD1MAPTP2RY1 | |
| SCHEMBL11922572 | 0.71 | FPR2 (0.48) | DRD1ALDH1A1MAPTATMP2RY1 | |
| SCHEMBL12303852 | 0.71 | KCNH2 (0.44) | DRD1KCNH2P2RY1 | |
| SCHEMBL12303690 | 0.70 | TDP1 (0.49) | DRD1KCNH2ALDH1A1MAPTATM | |
| SCHEMBL11922573 | 0.70 | CFTR (0.51) | DRD1ALDH1A1MAPTATMP2RY1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011032277-A1 | QUINAZOLINONE DERIVATIVES AS VIRAL POLYMERASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-03-24 | — | — | WO | disclosed |