Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 14/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 10/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12303953 | 0.81 | CYP11B1 (0.47) | CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL14451615 | 0.77 | CYP19A1 (0.50) | CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL28869336 | 0.75 | CYP11B1 (0.58) | CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL14414468 | 0.74 | CYP19A1 (0.56) | CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL9610932 | 0.72 | CYP11B1 (0.54) | CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL12332513 | 0.72 | KIF11 (0.36) | — | |
| SCHEMBL28537887 | 0.71 | CYP11B1 (0.53) | CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL28101470 | 0.67 | CYP11B1 (0.74) | CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL11919267 | 0.67 | CYP11B1 (0.60) | CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL306338 | 0.67 | CYP11B1 (0.73) | CYP11B1CYP11B2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011032277-A1 | QUINAZOLINONE DERIVATIVES AS VIRAL POLYMERASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-03-24 | — | — | WO | disclosed |