Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | LPL | P06858 | 1/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18747194 | 0.86 | HTR2A (0.48) | HSD17B10TP53LPLLIPGCYP3A4 | |
| SCHEMBL13083296 | 0.85 | RARB (0.47) | CNR1CNR2HSD17B10NPC1TP53 | |
| SCHEMBL530305 | 0.80 | CNR1 (0.48) | CNR1CNR2HSD17B10NPC1TP53 | |
| SCHEMBL530150 | 0.79 | PNMT (0.45) | CNR1CNR2HSD17B10NPC1TP53 | |
| Ammonia Solution, Strong SCHEMBL6193068 | 0.78 | CNR1 (0.47) | CNR1CNR2HSD17B10NPC1TP53 | |
| Ammonia Solution, Strong SCHEMBL6341561 | 0.78 | PNMT (0.44) | CNR1CNR2HSD17B10NPC1TP53 | |
| SCHEMBL9921243 | 0.77 | DAO (0.50) | CNR1CNR2HSD17B10NPC1TP53 | |
| SCHEMBL22296004 | 0.77 | SKP2 (0.46) | CNR1CNR2LPLLIPGALOX5 | |
| SCHEMBL14049425 | 0.75 | CNR1 (0.59) | CNR1CNR2HSD17B10NPC1TP53 | |
| SCHEMBL1524010 | 0.75 | CNR1 (0.64) | CNR1CNR2HSD17B10TP53TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019149734-A1 | CYCLOALKYL SUBSTITUTED PYRAZOLOPYRIMIDINES HAVING ACTIVITY AGAINST RSV | Janssen Sciences Ireland Unlimited Company (IE) | 2019-08-08 | — | — | WO | disclosed |
| WO-2011032277-A1 | QUINAZOLINONE DERIVATIVES AS VIRAL POLYMERASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-03-24 | — | — | WO | disclosed |