Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PRCP | P42785 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PREP | P48147 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4849095 | 0.89 | HTT (0.48) | MITFMAPTHTTALDH1A1TSHR | |
| SCHEMBL4849092 | 0.89 | HTT (0.48) | MITFMAPTHTTALDH1A1TSHR | |
| SCHEMBL10741414 | 0.80 | NPC1 (0.46) | ALDH1A1NPSR1PREPSMN1; SMN2NPC1 | |
| SCHEMBL18020339 | 0.79 | MITF (0.49) | MITFMAPTHTTALDH1A1TSHR | |
| SCHEMBL204603 | 0.78 | MITF (0.48) | MITFMAPTHTTALDH1A1TSHR | |
| SCHEMBL8298601 | 0.78 | MITF (0.48) | MITFMAPTHTTALDH1A1TSHR | |
| SCHEMBL8279227 | 0.78 | MITF (0.48) | MITFMAPTHTTALDH1A1TSHR | |
| SCHEMBL2707991 | 0.78 | MITF (0.48) | MITFMAPTHTTALDH1A1TSHR | |
| SCHEMBL201194 | 0.76 | HTT (0.47) | MITFMAPTHTTALDH1A1TSHR | |
| SCHEMBL9977347 | 0.76 | HTT (0.47) | MITFMAPTHTTALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011028596-A1 | CHEMICAL COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2011-03-10 | — | — | WO | disclosed |