Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 8/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | FAP | Q12884 | 1/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1953168 | 1.00 | EPHX1 (0.47) | EPHX1SMN1; SMN2ALDH1A1ATMRAB9A | |
| SCHEMBL1953167 | 1.00 | EPHX1 (0.47) | EPHX1SMN1; SMN2ALDH1A1ATMRAB9A | |
| SCHEMBL12311005 | 0.98 | EPHX1 (0.50) | EPHX1SMN1; SMN2ALDH1A1ATMRAB9A | |
| SCHEMBL8455512 | 0.98 | EPHX1 (0.50) | EPHX1SMN1; SMN2ALDH1A1ATMRAB9A | |
| SCHEMBL25069101 | 0.96 | EPHX1 (0.43) | EPHX1SMN1; SMN2ALDH1A1ATMRAB9A | |
| SCHEMBL5967831 | 0.92 | SMYD3 (0.46) | EPHX1SMN1; SMN2ALDH1A1ATMDPP4 | |
| SCHEMBL15054947 | 0.92 | SMYD3 (0.46) | EPHX1SMN1; SMN2ALDH1A1ATMDPP4 | |
| SCHEMBL28661580 | 0.92 | SMYD3 (0.46) | EPHX1SMN1; SMN2ALDH1A1ATMDPP4 | |
| SCHEMBL2735532 | 0.86 | CPB2 (0.40) | EPHX1SMN1; SMN2ALDH1A1ATMKDM4E | |
| SCHEMBL2735524 | 0.85 | KMT2A (0.48) | EPHX1SMN1; SMN2ALDH1A1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011031934-A1 | HEPATITIS C VIRUS INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2011-03-17 | — | — | WO | disclosed |