Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12824606 | 0.88 | ALDH1A1 (0.71) | ALDH1A1TDP1MAPTKCNJ1KDM4E | |
| SCHEMBL12824361 | 0.82 | ALDH1A1 (0.96) | ALDH1A1TDP1MAPTKCNJ1KDM4E | |
| SCHEMBL1852489 | 0.81 | ALDH1A1 (0.70) | ALDH1A1TDP1MAPTKCNJ1KDM4E | |
| SCHEMBL12515889 | 0.80 | ALDH1A1 (1.00) | ALDH1A1TDP1MAPTKCNJ1KDM4E | |
| SCHEMBL13711958 | 0.80 | ALDH1A1 (1.00) | ALDH1A1TDP1MAPTKCNJ1KDM4E | |
| SCHEMBL12744156 | 0.75 | ALDH1A1 (0.36) | ALDH1A1TDP1MAPTKDM4EGAA | |
| SCHEMBL12824499 | 0.72 | ALDH1A1 (0.72) | ALDH1A1TDP1MAPTKCNJ1KDM4E | |
| SCHEMBL7231518 | 0.71 | ALDH1A1 (0.70) | ALDH1A1TDP1MAPTKCNJ1KDM4E | |
| SCHEMBL1554083 | 0.71 | TDP1 (1.00) | ALDH1A1TDP1MAPTKCNJ1MEN1 | |
| SCHEMBL12744157 | 0.68 | NPC1 (0.41) | ALDH1A1TDP1L3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7910579-B2 | Benzoxazole derivatives | TOHOKU UNIVERSITY (JP) | 2011-03-22 | — | — | US | disclosed |
| US-20100021385-A1 | BENZOXAZOLE DERIVATIVES | TOHOKU UNIVERSITY (JP) | 2010-01-28 | — | — | US | disclosed |
| EP-2103611-A1 | BENZOXAZOLE DERIVATIVES | Tohoku University (JP) | 2009-09-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100021385-A1 | BENZOXAZOLE DERIVATIVES | CBX7, KIT, BMX | ALDH1A1 1195/4885TDP1 1704/4885MAPT 1385/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.